Gut microbiota transfer from autoimmune dry eye mice imprints stereotypic B cell receptor repertoires in the lacrimal gland and induces disease.

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Title: Gut microbiota transfer from autoimmune dry eye mice imprints stereotypic B cell receptor repertoires in the lacrimal gland and induces disease.
Authors: Kim S; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Lee S; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea., Ju S; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Bae J; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Ryu JS; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Heo Y; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Choi WJ; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Shin KJ; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Kim SJ; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Kim N; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea., Choi H; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Park J; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee E; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Yoon CH; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kwon S; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.; Interdisciplinary Program in Bioengineering, Seoul National University, Seoul, Republic of Korea.; Bio-MAX Institute, Seoul National University, Seoul, Republic of Korea., Chung J; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.; Institute on Aging, Seoul National University, Seoul, Republic of Korea., Kim MK; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Transplantation Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 16; Vol. 17, pp. 1827057. Date of Electronic Publication: 2026 Jun 16 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1827057