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Gut microbiota transfer from autoimmune dry eye mice imprints stereotypic B cell receptor repertoires in the lacrimal gland and induces disease.

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Title: Gut microbiota transfer from autoimmune dry eye mice imprints stereotypic B cell receptor repertoires in the lacrimal gland and induces disease.
Authors: Kim S; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Lee S; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea., Ju S; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Bae J; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Ryu JS; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Heo Y; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Choi WJ; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Shin KJ; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Kim SJ; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Kim N; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea., Choi H; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea., Park J; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee E; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea., Yoon CH; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kwon S; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.; Interdisciplinary Program in Bioengineering, Seoul National University, Seoul, Republic of Korea.; Bio-MAX Institute, Seoul National University, Seoul, Republic of Korea., Chung J; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.; Institute on Aging, Seoul National University, Seoul, Republic of Korea., Kim MK; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Transplantation Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Source: Frontiers in immunology [Front Immunol] 2026 Jun 16; Vol. 17, pp. 1827057. Date of Electronic Publication: 2026 Jun 16 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Gut microbiota transfer from autoimmune dry eye mice imprints stereotypic B cell receptor repertoires in the lacrimal gland and induces disease.
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  Data: <searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ju+S%22">Ju S</searchLink>; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bae+J%22">Bae J</searchLink>; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryu+JS%22">Ryu JS</searchLink>; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Heo+Y%22">Heo Y</searchLink>; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+WJ%22">Choi WJ</searchLink>; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+KJ%22">Shin KJ</searchLink>; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SJ%22">Kim SJ</searchLink>; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+N%22">Kim N</searchLink>; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; R&D Center, Hecto Healthcare Co., Ltd., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+E%22">Lee E</searchLink>; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+CH%22">Yoon CH</searchLink>; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+S%22">Kwon S</searchLink>; Department of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.; Interdisciplinary Program in Bioengineering, Seoul National University, Seoul, Republic of Korea.; Bio-MAX Institute, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+J%22">Chung J</searchLink>; Department of Biomedical Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.; Institute on Aging, Seoul National University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MK%22">Kim MK</searchLink>; Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Transplantation Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jun 16; Vol. 17, pp. 1827057. <i>Date of Electronic Publication: </i>2026 Jun 16 (<i>Print Publication: </i>2026).
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        Value: 10.3389/fimmu.2026.1827057
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        Text: English
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