Site-specific trastuzumab Fab-DM1 via butelase-1 with ABD fusion for potent HER2-positive tumor control.

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Title: Site-specific trastuzumab Fab-DM1 via butelase-1 with ABD fusion for potent HER2-positive tumor control.
Authors: Han Y; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Guo Q; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.; School of Basic Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan, P.R. China., Cao H; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Qin T; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Zhang X; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Dong Q; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Huang Y; Clinical Systems Biology Laboratories, Translational Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Hanan, P.R. China., Mao Y; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Wang Z; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Liu Q; School of Life Sciences, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, P.R. China., Liu Y; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China. liuyangxue1224@zzu.edu.cn., Zhang S; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China. zhangst@zzu.edu.cn.; School of Life Sciences, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, P.R. China. zhangst@zzu.edu.cn.
Source: Medical oncology (Northwood, London, England) [Med Oncol] 2026 Jul 01; Vol. 43 (8). Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1559-131X
DOI:10.1007/s12032-026-03317-3