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Site-specific trastuzumab Fab-DM1 via butelase-1 with ABD fusion for potent HER2-positive tumor control.

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Title: Site-specific trastuzumab Fab-DM1 via butelase-1 with ABD fusion for potent HER2-positive tumor control.
Authors: Han Y; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Guo Q; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.; School of Basic Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan, P.R. China., Cao H; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Qin T; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Zhang X; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Dong Q; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Huang Y; Clinical Systems Biology Laboratories, Translational Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Hanan, P.R. China., Mao Y; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Wang Z; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China., Liu Q; School of Life Sciences, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, P.R. China., Liu Y; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China. liuyangxue1224@zzu.edu.cn., Zhang S; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China. zhangst@zzu.edu.cn.; School of Life Sciences, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, P.R. China. zhangst@zzu.edu.cn.
Source: Medical oncology (Northwood, London, England) [Med Oncol] 2026 Jul 01; Vol. 43 (8). Date of Electronic Publication: 2026 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Site-specific trastuzumab Fab-DM1 via butelase-1 with ABD fusion for potent HER2-positive tumor control.
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  Data: <searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Guo+Q%22">Guo Q</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.; School of Basic Medicine, Henan University of Chinese Medicine, Zhengzhou, 450046, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Cao+H%22">Cao H</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Qin+T%22">Qin T</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Dong+Q%22">Dong Q</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Clinical Systems Biology Laboratories, Translational Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Hanan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Mao+Y%22">Mao Y</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; School of Life Sciences, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, P.R. China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China. liuyangxue1224@zzu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Longhu Laboratory of Advanced Immunology, School of Life Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, P.R. China. zhangst@zzu.edu.cn.; School of Life Sciences, Henan Institute of Science and Technology, Xinxiang, 453003, Henan, P.R. China. zhangst@zzu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229435512%22">Medical oncology (Northwood, London, England)</searchLink> [Med Oncol] 2026 Jul 01; Vol. 43 (8). <i>Date of Electronic Publication: </i>2026 Jul 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9435512 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1559-131X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213570560%22">13570560 </searchLink><i>NLM ISO Abbreviation: </i>Med Oncol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 01
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