Neurotensin receptor 2 agonism attenuates adverse cardiac remodeling in preclinical models.
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| Title: | Neurotensin receptor 2 agonism attenuates adverse cardiac remodeling in preclinical models. |
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| Authors: | Shiva N; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Kawase H; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; Department of Cardiology, Nagoya University School of Medicine, Nagoya, Japan., Einsiedel J; Department of Chemistry and Pharmacy, Friedrich Alexander University, Erlangen, Germany., Kwon J; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Kumar S; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Shao J; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Du Z; Circadian Regulation of Cardiometabolism Lab, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Frankfurt am Main, Germany.; Cardiopulmonary Institute, Goethe University, Frankfurt am Main, Germany., Kubin N; Department of Cardiology, Campus Kerckhoff, Bad Nauheim and Medical Clinic I, Justus-Liebig-University Giessen, Giessen, Germany., Shimari M; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Günther S; Deep Sequencing Platform, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Li T; Department of Biochemistry and Physiology, Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Dierickx P; Circadian Regulation of Cardiometabolism Lab, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Frankfurt am Main, Germany.; Cardiopulmonary Institute, Goethe University, Frankfurt am Main, Germany., Sossalla S; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Frankfurt am Main, Germany.; Department of Cardiology, Campus Kerckhoff, Bad Nauheim and Medical Clinic I, Justus-Liebig-University Giessen, Giessen, Germany., Offermanns S; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Frankfurt am Main, Germany.; Cardiopulmonary Institute, Goethe University, Frankfurt am Main, Germany.; Centre for Molecular Medicine, Medical Faculty, Goethe University, Frankfurt am Main, Germany., Gmeiner P; Department of Chemistry and Pharmacy, Friedrich Alexander University, Erlangen, Germany., Wettschureck N; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Frankfurt am Main, Germany.; Cardiopulmonary Institute, Goethe University, Frankfurt am Main, Germany.; Centre for Molecular Medicine, Medical Faculty, Goethe University, Frankfurt am Main, Germany. |
| Source: | Science translational medicine [Sci Transl Med] 2026 Jul; Vol. 18 (856), pp. eaea9877. Date of Electronic Publication: 2026 Jul 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.aea9877 |
