Osimertinib-induced cardiotoxicity is driven by HDAC-dependent epigenetic repression and rescued by vorinostat.
Saved in:
| Title: | Osimertinib-induced cardiotoxicity is driven by HDAC-dependent epigenetic repression and rescued by vorinostat. |
|---|---|
| Authors: | Toro Cora A; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Bhati AS; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Titus AS; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Jaiswal A; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Singh B; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Umbarkar P; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Li DY; Division of Cardiovascular Disease, The University of Alabama at Birmingham, Birmingham, AL, USA., Dutta R; Division of Cardiovascular Disease, The University of Alabama at Birmingham, Birmingham, AL, USA., Zhang Q; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Verma SK; Division of Cardiovascular Disease, The University of Alabama at Birmingham, Birmingham, AL, USA., Tousif S; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA., Lal H; Department of Cellular Biology & Anatomy, LSU Health Shreveport, Shreveport, LA, USA. Hind.lal@lsuhs.edu. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jul 02; Vol. 11 (1). Date of Electronic Publication: 2026 Jul 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 2059-3635 |
|---|---|
| DOI: | 10.1038/s41392-026-02814-1 |
