DNA methylation clock in bull sperm cells reveals the epigenetic aging characteristics and impact on fertility.

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Title: DNA methylation clock in bull sperm cells reveals the epigenetic aging characteristics and impact on fertility.
Authors: Li W; National Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Tang Y; National Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., An S; National Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Wang J; National Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Feng X; National Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China., Chen S; National Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. sqchen1028@163.com., Yu Y; National Engineering Laboratory for Animal Breeding, State Key Laboratory of Animal Biotech Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. yuying@cau.edu.cn.
Source: Journal of animal science and biotechnology [J Anim Sci Biotechnol] 2026 Jul 02; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101581293 Publication Model: Electronic Cited Medium: Print ISSN: 1674-9782 (Print) Linking ISSN: 16749782 NLM ISO Abbreviation: J Anim Sci Biotechnol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1674-9782
DOI:10.1186/s40104-026-01444-5