SMPD4 deficiency disrupts indirect neurogenesis and neuronal migration in gyrencephalic cortex.

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Title: SMPD4 deficiency disrupts indirect neurogenesis and neuronal migration in gyrencephalic cortex.
Authors: Wang CX; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China., Yang FW; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China., Zhao MM; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China., Tong SY; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China., Lin YN; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China., Cao JW; School of life and health sciences, Hunan University of Science and Technology, Xiangtan, 411100, China., Fu Y; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China., Wang J; Department of Neurology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China., Shao Z; Department of Neurology, Zhongshan Hospital, Institute for Translational Brain Research, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200032, China., Liu LY; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China., Yu YC; Jing'an District Central Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Shanghai Key Laboratory of Gene Editing and Cell Therapy for Rare Diseases, Fudan University, Shanghai, 200032, China.; Advanced Model Animal Research Center, Department of Biotechnology and Biomedicine, Yangtze Delta Region Institute of Tsinghua University, Jiaxing, 314006, China.
Source: Brain : a journal of neurology [Brain] 2026 Jul 02. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1460-2156
DOI:10.1093/brain/awag236