The cholesterol-dependent cytolysin promotes Streptococcus systemic spread and induces arachidonic acid accumulation-mediated lethality in a murine intraperitoneal infection model.
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| Title: | The cholesterol-dependent cytolysin promotes Streptococcus systemic spread and induces arachidonic acid accumulation-mediated lethality in a murine intraperitoneal infection model. |
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| Authors: | Xia L; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China., Tian X; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China., Yuan C; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China., Zhu Z; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China., Pan F; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China., Fan H; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China., Hullahalli K; Division of Infectious Diseases, Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA., Waldor MK; Division of Infectious Diseases, Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA., Ma Z; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China. |
| Source: | Infection and immunity [Infect Immun] 2026 Jul 14; Vol. 94 (7), pp. e0016426. Date of Electronic Publication: 2026 Jun 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0246127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5522 (Electronic) Linking ISSN: 00199567 NLM ISO Abbreviation: Infect Immun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42390106 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The cholesterol-dependent cytolysin promotes Streptococcus systemic spread and induces arachidonic acid accumulation-mediated lethality in a murine intraperitoneal infection model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Xia+L%22">Xia L</searchLink>; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Tian+X%22">Tian X</searchLink>; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Yuan+C%22">Yuan C</searchLink>; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Pan+F%22">Pan F</searchLink>; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Fan+H%22">Fan H</searchLink>; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Hullahalli+K%22">Hullahalli K</searchLink>; Division of Infectious Diseases, Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Waldor+MK%22">Waldor MK</searchLink>; Division of Infectious Diseases, Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ma+Z%22">Ma Z</searchLink>; Ministry of Agriculture Key Laboratory of Animal Bacteriology, the International Joint Laboratory of Animal Health and Food Safety, and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220246127%22">Infection and immunity</searchLink> [Infect Immun] 2026 Jul 14; Vol. 94 (7), pp. e0016426. <i>Date of Electronic Publication: </i>2026 Jun 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+For+Microbiology%22">American Society For Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0246127 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-5522 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200199567%22">00199567 </searchLink><i>NLM ISO Abbreviation: </i>Infect Immun <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42390106 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1128/iai.00164-26 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0016426 Titles: – TitleFull: The cholesterol-dependent cytolysin promotes Streptococcus systemic spread and induces arachidonic acid accumulation-mediated lethality in a murine intraperitoneal infection model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Xia L – PersonEntity: Name: NameFull: Tian X – PersonEntity: Name: NameFull: Yuan C – PersonEntity: Name: NameFull: Zhu Z – PersonEntity: Name: NameFull: Pan F – PersonEntity: Name: NameFull: Fan H – PersonEntity: Name: NameFull: Hullahalli K – PersonEntity: Name: NameFull: Waldor MK – PersonEntity: Name: NameFull: Ma Z IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 07 Text: 2026 Jul 14 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1098-5522 Numbering: – Type: volume Value: 94 – Type: issue Value: 7 Titles: – TitleFull: Infection and immunity Type: main |
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