Cost-effectiveness of the sFlt-1/PlGF ratio and telemonitoring in managing suspected pre-eclampsia: protocol for the PREPARE II randomised controlled trial.

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Title: Cost-effectiveness of the sFlt-1/PlGF ratio and telemonitoring in managing suspected pre-eclampsia: protocol for the PREPARE II randomised controlled trial.
Authors: Wind M; Department of Obstetrics, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands m.wind@lumc.nl., Peters A; Department of Obstetrics, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands., van den Akker-van Marle ME; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands., Vanden Auweele K; Patient' Association, The Hellp Foundation, Zwolle, Overijssel, the Netherlands., van Bodegom-Vos L; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands., Boekhorst F; Department of Obstetrics, Groene Hart Hospital, Gouda, Zuid-Holland, the Netherlands., Cobbaert CM; Department of Clinical Chemistry, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands., Hermes W; Department of Obstetrics, Haaglanden Medical Center, The Hague, Zuid-Holland, the Netherlands., Van Hoorn ME; Department of Obstetrics, Haga Hospital, The Hague, Zuid-Holland, the Netherlands., Van Den Haak L; Department of Obstetrics, Reinier de Graaf Hospital, Delft, Zuid-Holland, the Netherlands., Lutke Holzik M; Department of Obstetrics, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands., Tsonaka R; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands., Van Wyk L; Department of Obstetrics, Alrijne Hospital, Leiden, Zuid-Holland, the Netherlands., Teng YKO; Department of Nephrology, Leiden University Medical Center, Leiden, ZH, the Netherlands., Sueters M; Department of Obstetrics, Leiden University Medical Center, Leiden, Zuid-Holland, the Netherlands.
Source: BMJ open [BMJ Open] 2026 Jul 02; Vol. 16 (7), pp. e113516. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-113516