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Association of cytochrome P450 2C19 genotypes with effectiveness of clopidogrel in ischemic stroke by smoking status.

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Title: Association of cytochrome P450 2C19 genotypes with effectiveness of clopidogrel in ischemic stroke by smoking status.
Authors: Park H; Department of Neurology, School of Medicine,, Kyungpook National University , Daegu, Republic of Korea.; Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea., Lee HS; Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea., Jung YH; Department of Neurology, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea.; Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Republic of Korea., Jeon S; Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim J; Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Park HK; Department of Neurology, Inha University School of Medicine, Incheon, Republic of Korea., Han SW; Department of Neurology, Inje University College of Medicine, Sanggye Paik Hospital, Seoul, Republic of Korea., Kim YD; Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea., Park JH; Department of Neurology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea., Cha JK; Department of Neurology, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Republic of Korea., Park HY; Department of Neurology, Wonkwang University School of Medicine, Wonkwang University Hospital, Iksan, Republic of Korea., Sohn SI; Department of Neurology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea., Yu S; Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea., Lee JH; Department of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea., Shin DH; Department of Neurology, Gachon University Gil Medical Center, Incheon, Republic of Korea., Kim EG; Department of Neurology, Inje University Busan Paik Hospital, Busan, Republic of Korea., Lee KY; Department of Neurology, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea. kylee@yuhs.ac.; Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Republic of Korea. kylee@yuhs.ac., Song TJ; Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea. knstar@ewha.ac.kr.; Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, Republic of Korea. knstar@ewha.ac.kr.
Corporate Authors: PLATELET Trial Investigators
Source: Scientific reports [Sci Rep] 2026 Jul 02. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Park+H%22">Park H</searchLink>; Department of Neurology, School of Medicine,, Kyungpook National University , Daegu, Republic of Korea.; Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HS%22">Lee HS</searchLink>; Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+YH%22">Jung YH</searchLink>; Department of Neurology, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea.; Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+S%22">Jeon S</searchLink>; Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+HK%22">Park HK</searchLink>; Department of Neurology, Inha University School of Medicine, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+SW%22">Han SW</searchLink>; Department of Neurology, Inje University College of Medicine, Sanggye Paik Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YD%22">Kim YD</searchLink>; Department of Neurology, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; Department of Neurology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cha+JK%22">Cha JK</searchLink>; Department of Neurology, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+HY%22">Park HY</searchLink>; Department of Neurology, Wonkwang University School of Medicine, Wonkwang University Hospital, Iksan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+SI%22">Sohn SI</searchLink>; Department of Neurology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yu+S%22">Yu S</searchLink>; Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Department of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+DH%22">Shin DH</searchLink>; Department of Neurology, Gachon University Gil Medical Center, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+EG%22">Kim EG</searchLink>; Department of Neurology, Inje University Busan Paik Hospital, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KY%22">Lee KY</searchLink>; Department of Neurology, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea. kylee@yuhs.ac.; Severance Institute for Vascular and Metabolic Research, Yonsei University College of Medicine, Seoul, Republic of Korea. kylee@yuhs.ac.<br /><searchLink fieldCode="AU" term="%22Song+TJ%22">Song TJ</searchLink>; Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea. knstar@ewha.ac.kr.; Graduate Program in System Health Science and Engineering, Ewha Womans University, Seoul, Republic of Korea. knstar@ewha.ac.kr.
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