Adcyap1r1-driven astrocyte reprogramming attenuates neuroinflammation and promotes dopaminergic neuroprotection in Parkinson's Disease.

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Title: Adcyap1r1-driven astrocyte reprogramming attenuates neuroinflammation and promotes dopaminergic neuroprotection in Parkinson's Disease.
Authors: Zheng YY; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China.; School of Basic Medical, Shandong Medical and Pharmaceutical University, Yantai, 264003, China., Hu LR; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Gu Y; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Cai MY; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Wang XW; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Chen WF; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China. chenwenfangqd@163.com.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2026 Jul 02. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1757-6512
DOI:10.1186/s13287-026-05133-y