Adcyap1r1-driven astrocyte reprogramming attenuates neuroinflammation and promotes dopaminergic neuroprotection in Parkinson's Disease.

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Title: Adcyap1r1-driven astrocyte reprogramming attenuates neuroinflammation and promotes dopaminergic neuroprotection in Parkinson's Disease.
Authors: Zheng YY; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China.; School of Basic Medical, Shandong Medical and Pharmaceutical University, Yantai, 264003, China., Hu LR; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Gu Y; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Cai MY; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Wang XW; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China., Chen WF; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China. chenwenfangqd@163.com.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2026 Jul 02. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Adcyap1r1-driven astrocyte reprogramming attenuates neuroinflammation and promotes dopaminergic neuroprotection in Parkinson's Disease.
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  Data: <searchLink fieldCode="AU" term="%22Zheng+YY%22">Zheng YY</searchLink>; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China.; School of Basic Medical, Shandong Medical and Pharmaceutical University, Yantai, 264003, China.<br /><searchLink fieldCode="AU" term="%22Hu+LR%22">Hu LR</searchLink>; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Gu+Y%22">Gu Y</searchLink>; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Cai+MY%22">Cai MY</searchLink>; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Wang+XW%22">Wang XW</searchLink>; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China.<br /><searchLink fieldCode="AU" term="%22Chen+WF%22">Chen WF</searchLink>; Department of Physiology, Shandong Key Laboratory of Pathogenesis and Prevention of Brain Disorders, State Key Disciplines: Physiology, School of Basic Medicine, Qingdao University, Qingdao, 266071, China. chenwenfangqd@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101527581%22">Stem cell research & therapy</searchLink> [Stem Cell Res Ther] 2026 Jul 02. <i>Date of Electronic Publication: </i>2026 Jul 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101527581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-6512 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217576512%22">17576512 </searchLink><i>NLM ISO Abbreviation: </i>Stem Cell Res Ther <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1186/s13287-026-05133-y
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: Adcyap1r1-driven astrocyte reprogramming attenuates neuroinflammation and promotes dopaminergic neuroprotection in Parkinson's Disease.
        Type: main
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            NameFull: Zheng YY
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            NameFull: Hu LR
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            NameFull: Gu Y
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            NameFull: Cai MY
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            NameFull: Wang XW
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            NameFull: Chen WF
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          Dates:
            – D: 02
              M: 07
              Text: 2026 Jul 02
              Type: published
              Y: 2026
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              Value: 1757-6512
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            – TitleFull: Stem cell research & therapy
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