A Non-Canonical Role for Hepatocyte MLKL in Promoting Mitochondrial Dysfunction and Senescence in the Aging Liver.
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| Title: | A Non-Canonical Role for Hepatocyte MLKL in Promoting Mitochondrial Dysfunction and Senescence in the Aging Liver. |
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| Authors: | Mohammed S; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Jiang C; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Pennington T; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA., Bhaskaran S; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Ohene-Marfo P; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Kneuper KF; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Georgescu C; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA., Pitts K; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Division of Digestive Diseases and Nutrition, Department of Medicine, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Tran A; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Peng Z; Department of Chemistry and Biochemistry, The University of Oklahoma, Norman, Oklahoma, USA., Singh A; Department of Chemistry and Biochemistry, The University of Oklahoma, Norman, Oklahoma, USA., Yang Z; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Department of Chemistry and Biochemistry, The University of Oklahoma, Norman, Oklahoma, USA., Li T; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Harold Hamm Diabetes Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Hannafon B; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Department of Obstetrics and Gynecology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Houchen C; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Division of Digestive Diseases and Nutrition, Department of Medicine, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Wren JD; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA., Yabluchanskiy A; Department of Neurosurgery, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Galvan V; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Oklahoma Center for Geroscience & Healthy Brain Aging, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA., Ahsan N; Department of Chemistry and Biochemistry, The University of Oklahoma, Norman, Oklahoma, USA.; Mass Spectrometry, Proteomics and Metabolomics Core Facility, Stephenson Life Sciences Research Center, The University of Oklahoma, Norman, Oklahoma, USA., Kinter M; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA., Lewis TL Jr; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Aging & Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA., Deepa SS; Stephenson Cancer Center, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Department of Biochemistry & Physiology, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA.; Oklahoma Center for Geroscience & Healthy Brain Aging, University of Oklahoma Health Campus, Oklahoma City, Oklahoma, USA. |
| Source: | Aging cell [Aging Cell] 2026 Jul; Vol. 25 (7), pp. e70618. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1474-9726 |
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| DOI: | 10.1111/acel.70618 |
