Pilot spatial transcriptomics of dental pulpitis suggests immune-fibroblast profiling linked to reversibility.

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Bibliographic Details
Title: Pilot spatial transcriptomics of dental pulpitis suggests immune-fibroblast profiling linked to reversibility.
Authors: Zaky S; Department of Oral and Craniofacial Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA. shz33@pitt.edu.; Center for Craniofacial Regeneration, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA. shz33@pitt.edu., Rajasundaram D; Department of Pediatrics, Division of Health Informatics, Children's Hospital of Pittsburgh, Pittsburgh, USA.; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, USA., Lee AL; Institute for Quantitative Biomedicine, Rutgers University, Piscataway, New Jersey, USA., Summersgill K; Department of Diagnostic Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA., Levine S; Department of Diagnostic Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA., Boulos O; Department of Diagnostic Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA., Dunn S; Department of Diagnostic Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA., Intini G; Center for Craniofacial Regeneration, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA.; Department of Periodontics and Preventive Dentistry, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA.; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, USA., Sfeir C; Center for Craniofacial Regeneration, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA.; Department of Periodontics and Preventive Dentistry, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA.; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, USA., Silva R; Department of Endodontics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, USA. renato.silva@pitt.edu.
Source: Journal of translational medicine [J Transl Med] 2026 Jul 03; Vol. 24 (1). Date of Electronic Publication: 2026 Jul 03.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1479-5876
DOI:10.1186/s12967-026-08520-4