View in EDS

Repurposing Metformin to Promote Fracture Callus Maturation via AMPK-Driven Metabolic Activation.

Saved in:
Bibliographic Details
Title: Repurposing Metformin to Promote Fracture Callus Maturation via AMPK-Driven Metabolic Activation.
Authors: Pastukh V; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Zhang J; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Alexander PG; Joint Tissue Development and Engineering Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Bhargava S; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Shams A; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Zhao C; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Hogan MV; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Wang JH; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Source: Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2026 Jul; Vol. 44 (7), pp. e70246.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8404726 Publication Model: Print Cited Medium: Internet ISSN: 1554-527X (Electronic) Linking ISSN: 07360266 NLM ISO Abbreviation: J Orthop Res Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42400344
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Repurposing Metformin to Promote Fracture Callus Maturation via AMPK-Driven Metabolic Activation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Pastukh+V%22">Pastukh V</searchLink>; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Alexander+PG%22">Alexander PG</searchLink>; Joint Tissue Development and Engineering Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bhargava+S%22">Bhargava S</searchLink>; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Shams+A%22">Shams A</searchLink>; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+C%22">Zhao C</searchLink>; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hogan+MV%22">Hogan MV</searchLink>; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Wang+JH%22">Wang JH</searchLink>; MechanoBiology Laboratory, Bethel Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228404726%22">Journal of orthopaedic research : official publication of the Orthopaedic Research Society</searchLink> [J Orthop Res] 2026 Jul; Vol. 44 (7), pp. e70246.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8404726 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1554-527X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207360266%22">07360266 </searchLink><i>NLM ISO Abbreviation: </i>J Orthop Res <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42400344
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/jor.70246
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e70246
    Titles:
      – TitleFull: Repurposing Metformin to Promote Fracture Callus Maturation via AMPK-Driven Metabolic Activation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Pastukh V
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Alexander PG
      – PersonEntity:
          Name:
            NameFull: Bhargava S
      – PersonEntity:
          Name:
            NameFull: Shams A
      – PersonEntity:
          Name:
            NameFull: Zhao C
      – PersonEntity:
          Name:
            NameFull: Hogan MV
      – PersonEntity:
          Name:
            NameFull: Wang JH
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1554-527X
          Numbering:
            – Type: volume
              Value: 44
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Journal of orthopaedic research : official publication of the Orthopaedic Research Society
              Type: main
ResultId 1