Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance.

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Title: Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance.
Authors: Menze I; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany. inga.menze@dzne.de.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany. inga.menze@dzne.de., Bernal J; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Department Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute for Neuroscience and Cardiovascular Research, Row Fogo Centre for Research into Ageing and The Brain, Department of Neuroimaging Sciences, The University of Edinburgh, Edinburgh, UK.; Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Kievit RA; Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Centre, Nijmegen, The Netherlands., Tripathi KP; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Kaleck T; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Yakupov R; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany., Altenstein S; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany., Bartels C; Department of Psychiatry and Psychotherapy, University Medical Centre Goettingen, Georg August University of Goettingen, Goettingen, Germany., Buerger K; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Butryn M; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany., Dechent P; MR-Research in Neurosciences, Department of Cognitive Neurology, University Medical Centre Goettingen, Goettingen, Germany., Ewers M; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Fliessbach K; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany., Frommann I; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany., Gemenetzi M; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany., Glanz W; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany., Gref D; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany., Hellmann-Regen J; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; Charité Universitätsmedizin Berlin, ECRC Experimental and Clinical Research Center, Berlin, Germany., Hetzer S; Berlin Centre for Advanced Neuroimaging, Charité - Universitätsmedizin Berlin, Berlin, Germany., Incesoy EI; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Vivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics, Vivantes Urban Hospital, Berlin, Germany., Janowitz D; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Kiliman I; German Centre for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Kleineidam L; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany., Kronmüller MT; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany., Laske C; German Centre for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., van Lent DM; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA., Lüsebrink F; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany., Perneczky R; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, Charing Cross Hospital, London, UK., Peters O; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; Charité Universitätsmedizin Berlin, ECRC Experimental and Clinical Research Center, Berlin, Germany., Preis L; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany., Priller J; Institute for Neuroscience and Cardiovascular Research, Row Fogo Centre for Research into Ageing and The Brain, Department of Neuroimaging Sciences, The University of Edinburgh, Edinburgh, UK.; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.; Department of Psychiatry and Psychotherapy, School of Medicine and Health, Technical University of Munich, and German Centre for Mental Health (DZPG), Munich, Germany., Rauchmann BS; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.; Department of Neuroradiology, University Hospital LMU, Munich, Germany., Rostamzadeh A; Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany., Roeske S; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany., Scheffler K; Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany., Schott BH; Department of Psychiatry and Psychotherapy, University Medical Centre Goettingen, Georg August University of Goettingen, Goettingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Leibniz Institute for Neurobiology, Magdeburg, Germany., Schneider A; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany., Sodenkamp S; German Centre for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Spottke A; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany., Spruth EJ; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany., Stark M; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany., Teipel S; German Centre for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Wagner M; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Centre Goettingen, Georg August University of Goettingen, Goettingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Campus Universitario de Santiago, Aveiro, Portugal., Jessen F; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., Ramirez A; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., Schreiber S; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany., Düzel E; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Institute of Cognitive Neuroscience, University College London, London, UK., Ziegler G; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Source: Nature communications [Nat Commun] 2026 Jul 04; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance.
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  Data: <searchLink fieldCode="AU" term="%22Menze+I%22">Menze I</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany. inga.menze@dzne.de.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany. inga.menze@dzne.de.<br /><searchLink fieldCode="AU" term="%22Bernal+J%22">Bernal J</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Department Artificial Intelligence in Biomedical Engineering (AIBE), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Institute for Neuroscience and Cardiovascular Research, Row Fogo Centre for Research into Ageing and The Brain, Department of Neuroimaging Sciences, The University of Edinburgh, Edinburgh, UK.; Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Kievit+RA%22">Kievit RA</searchLink>; Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Centre, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tripathi+KP%22">Tripathi KP</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kaleck+T%22">Kaleck T</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Yakupov+R%22">Yakupov R</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Altenstein+S%22">Altenstein S</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Bartels+C%22">Bartels C</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Centre Goettingen, Georg August University of Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Buerger+K%22">Buerger K</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Butryn+M%22">Butryn M</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dechent+P%22">Dechent P</searchLink>; MR-Research in Neurosciences, Department of Cognitive Neurology, University Medical Centre Goettingen, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ewers+M%22">Ewers M</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Fliessbach+K%22">Fliessbach K</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Frommann+I%22">Frommann I</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Gemenetzi+M%22">Gemenetzi M</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Glanz+W%22">Glanz W</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gref+D%22">Gref D</searchLink>; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hellmann-Regen+J%22">Hellmann-Regen J</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; Charité Universitätsmedizin Berlin, ECRC Experimental and Clinical Research Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hetzer+S%22">Hetzer S</searchLink>; Berlin Centre for Advanced Neuroimaging, Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Incesoy+EI%22">Incesoy EI</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Vivantes Klinikum Am Urban, Department of Psychiatry, Psychotherapy, and Psychosomatics, Vivantes Urban Hospital, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Janowitz+D%22">Janowitz D</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kiliman+I%22">Kiliman I</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Kleineidam+L%22">Kleineidam L</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Kronmüller+MT%22">Kronmüller MT</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Laske+C%22">Laske C</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22van+Lent+DM%22">van Lent DM</searchLink>; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lüsebrink+F%22">Lüsebrink F</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Perneczky+R%22">Perneczky R</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, Charing Cross Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Peters+O%22">Peters O</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.; Charité Universitätsmedizin Berlin, ECRC Experimental and Clinical Research Center, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Preis+L%22">Preis L</searchLink>; Department of Psychiatry and Neurosciences, Charité Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Priller+J%22">Priller J</searchLink>; Institute for Neuroscience and Cardiovascular Research, Row Fogo Centre for Research into Ageing and The Brain, Department of Neuroimaging Sciences, The University of Edinburgh, Edinburgh, UK.; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.; Department of Psychiatry and Psychotherapy, School of Medicine and Health, Technical University of Munich, and German Centre for Mental Health (DZPG), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Rauchmann+BS%22">Rauchmann BS</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.; Department of Neuroradiology, University Hospital LMU, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Rostamzadeh+A%22">Rostamzadeh A</searchLink>; Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Roeske+S%22">Roeske S</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Scheffler+K%22">Scheffler K</searchLink>; Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schott+BH%22">Schott BH</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Centre Goettingen, Georg August University of Goettingen, Goettingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Leibniz Institute for Neurobiology, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Sodenkamp+S%22">Sodenkamp S</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Spottke+A%22">Spottke A</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Spruth+EJ%22">Spruth EJ</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Stark+M%22">Stark M</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Teipel+S%22">Teipel S</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Centre Goettingen, Georg August University of Goettingen, Goettingen, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Goettingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Campus Universitario de Santiago, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Jessen+F%22">Jessen F</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Ramirez+A%22">Ramirez A</searchLink>; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Old Age Psychiatry and Cognitive Disorders, University of Bonn, University Hospital Bonn, Bonn, Germany.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Schreiber+S%22">Schreiber S</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Düzel+E%22">Düzel E</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.; Institute of Cognitive Neuroscience, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ziegler+G%22">Ziegler G</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.
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            NameFull: Kiliman I
      – PersonEntity:
          Name:
            NameFull: Kleineidam L
      – PersonEntity:
          Name:
            NameFull: Kronmüller MT
      – PersonEntity:
          Name:
            NameFull: Laske C
      – PersonEntity:
          Name:
            NameFull: van Lent DM
      – PersonEntity:
          Name:
            NameFull: Lüsebrink F
      – PersonEntity:
          Name:
            NameFull: Perneczky R
      – PersonEntity:
          Name:
            NameFull: Peters O
      – PersonEntity:
          Name:
            NameFull: Preis L
      – PersonEntity:
          Name:
            NameFull: Priller J
      – PersonEntity:
          Name:
            NameFull: Rauchmann BS
      – PersonEntity:
          Name:
            NameFull: Rostamzadeh A
      – PersonEntity:
          Name:
            NameFull: Roeske S
      – PersonEntity:
          Name:
            NameFull: Scheffler K
      – PersonEntity:
          Name:
            NameFull: Schott BH
      – PersonEntity:
          Name:
            NameFull: Schneider A
      – PersonEntity:
          Name:
            NameFull: Sodenkamp S
      – PersonEntity:
          Name:
            NameFull: Spottke A
      – PersonEntity:
          Name:
            NameFull: Spruth EJ
      – PersonEntity:
          Name:
            NameFull: Stark M
      – PersonEntity:
          Name:
            NameFull: Teipel S
      – PersonEntity:
          Name:
            NameFull: Wagner M
      – PersonEntity:
          Name:
            NameFull: Wiltfang J
      – PersonEntity:
          Name:
            NameFull: Jessen F
      – PersonEntity:
          Name:
            NameFull: Ramirez A
      – PersonEntity:
          Name:
            NameFull: Schreiber S
      – PersonEntity:
          Name:
            NameFull: Düzel E
      – PersonEntity:
          Name:
            NameFull: Ziegler G
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 04
              M: 07
              Text: 2026 Jul 04
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1