Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications.
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| Title: | Protein lactylation in health and diseases: molecular mechanisms, biological significance, and clinical implications. |
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| Authors: | Yang Y; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China., He Y; The First Department of Medical Oncology, The Fourth Affiliated Hospital of China Medical University, Shenyang, China., Zhang Z; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Zhang Y; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Gao R; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Du K; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China., Wu Y; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China., Wu J; Shenyang Key Laboratory of Chronic Disease Assessment and Nutritional Intervention for Heart and Brain, Shenyang Medical College, Shenyang, China. wuji@symc.edu.cn.; The Second Affiliated Hospital of Shenyang Medical College, Shenyang, China. wuji@symc.edu.cn., Wei M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China. minjie_wei@163.com.; Drug and Food Inspection and Testing Center, China Medical University, Shenyang, China. minjie_wei@163.com.; Liaoning Medical Diagnosis and Treatment Center, Shenyang, China. minjie_wei@163.com., Liu M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, China. saffer@163.com. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jul 06; Vol. 11 (1). Date of Electronic Publication: 2026 Jul 06. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2059-3635 |
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| DOI: | 10.1038/s41392-026-02757-7 |