Inhibition of the ZEB1-BCL2 axis in cancer-associated fibroblasts as a strategy to improve chemotherapy response in intrahepatic cholangiocarcinoma.
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| Title: | Inhibition of the ZEB1-BCL2 axis in cancer-associated fibroblasts as a strategy to improve chemotherapy response in intrahepatic cholangiocarcinoma. |
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| Authors: | Gonzalez-Sanchez E; HepatoBiliary Tumours Lab, Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer, CSIC-Universidad de Salamanca, Salamanca 37007, Spain; Department of Physiology and Pharmacology, University of Salamanca, Salamanca 37007, Spain; National Biomedical Research Institute on Liver and Gastrointestinal Diseases (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain., Vallette M; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris F-75012, France., Garcia-Collado L; HepatoBiliary Tumours Lab, Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer, CSIC-Universidad de Salamanca, Salamanca 37007, Spain., Ravichandra A; TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Germany., Minini M; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris F-75012, France; Université Paris Cité, CNRS, Inserm, NABI, Paris F-75006, France., Pavy A; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris F-75012, France., Amengual J; TGF-β and Cancer Group, Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Roldán-Hernández CA; HepatoBiliary Tumours Lab, Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer, CSIC-Universidad de Salamanca, Salamanca 37007, Spain., Ramirez AM; HepatoBiliary Tumours Lab, Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer, CSIC-Universidad de Salamanca, Salamanca 37007, Spain., Louis C; Inserm, Univ Rennes, OSS (Oncogenesis, Stress, Signaling) UMR_S 1242, Centre de Lutte contre le Cancer Eugène Marquis, Rennes F-35042, France., Lozano JJ; Bioinformatic Platform, CIBERehd, Barcelona, Spain., Fabregat I; National Biomedical Research Institute on Liver and Gastrointestinal Diseases (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain; TGF-β and Cancer Group, Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain., Guedj N; Service d'Anatomie Pathologique Hôpital Beaujon, Clichy F-92110, France; INSERM, UMR 1149, Centre de Recherche sur l'Inflammation, Paris F-75018, France., Paradis V; Service d'Anatomie Pathologique Hôpital Beaujon, Clichy F-92110, France; INSERM, UMR 1149, Centre de Recherche sur l'Inflammation, Paris F-75018, France., Coulouarn C; Inserm, Univ Rennes, OSS (Oncogenesis, Stress, Signaling) UMR_S 1242, Centre de Lutte contre le Cancer Eugène Marquis, Rennes F-35042, France., Aoudjehane L; ICAN BioCell-Human Liver Biology core, IHU - Foundation for innovation in Cardiometabolism and Nutrition (IHU-ICAN), Paris F-75013, France; Sorbonne Université, INSERM, UMRS 1166, Paris F-75013, France., Fouassier L; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris F-75012, France; Université Paris Cité, CNRS, Inserm, NABI, Paris F-75006, France. Electronic address: laura.fouassier@inserm.fr., Vaquero J; HepatoBiliary Tumours Lab, Centro de Investigación del Cáncer and Instituto de Biología Molecular y Celular del Cáncer, CSIC-Universidad de Salamanca, Salamanca 37007, Spain; National Biomedical Research Institute on Liver and Gastrointestinal Diseases (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: javier.vaquero@usal.es. |
| Source: | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Aug; Vol. 201, pp. 119741. Date of Electronic Publication: 2026 Jul 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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