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Shengxian decoction suppresses malignant progression of lung adenocarcinoma by enhancing CD8+ T cell function via the FYN-PI3K/AKT axis.

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Title: Shengxian decoction suppresses malignant progression of lung adenocarcinoma by enhancing CD8+ T cell function via the FYN-PI3K/AKT axis.
Authors: Ma Q; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China., Zeng X; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Huang C; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Liu X; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., He J; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Bai Y; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Xiong Y; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Tan S; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Mao Z; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Li X; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Wang Q; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China., Fu X; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. fuxi884853@163.com.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. fuxi884853@163.com., You F; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. yfmdoc@163.com.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. yfmdoc@163.com., Ren Y; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. ryftcm.dr@yahoo.com.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. ryftcm.dr@yahoo.com., Zheng C; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. zhengchuan@cdutcm.edu.cn.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. zhengchuan@cdutcm.edu.cn.; Sichuan Provincal Engineering Technology Research Center of Natural Small Molecule Drug, Tianfu TCM Innovation Harbour, Chengdu University of Traditional Chinese Medicine, Chengdu, 611930, China. zhengchuan@cdutcm.edu.cn.
Source: Chinese medicine [Chin Med] 2026 Jul 06; Vol. 21 (1). Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265109 Publication Model: Electronic Cited Medium: Print ISSN: 1749-8546 (Print) Linking ISSN: 17498546 NLM ISO Abbreviation: Chin Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Shengxian decoction suppresses malignant progression of lung adenocarcinoma by enhancing CD8<superscript>+</superscript> T cell function via the FYN-PI3K/AKT axis.
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  Data: <searchLink fieldCode="AU" term="%22Ma+Q%22">Ma Q</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Huang+C%22">Huang C</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Bai+Y%22">Bai Y</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Xiong+Y%22">Xiong Y</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Tan+S%22">Tan S</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Mao+Z%22">Mao Z</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China.<br /><searchLink fieldCode="AU" term="%22Fu+X%22">Fu X</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. fuxi884853@163.com.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. fuxi884853@163.com.<br /><searchLink fieldCode="AU" term="%22You+F%22">You F</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. yfmdoc@163.com.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. yfmdoc@163.com.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. ryftcm.dr@yahoo.com.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. ryftcm.dr@yahoo.com.<br /><searchLink fieldCode="AU" term="%22Zheng+C%22">Zheng C</searchLink>; Hospital of Chengdu University of Traditional Chinese Medicine, No.39, Shierqiao Road, Jinniu District, Chengdu, 610075, China. zhengchuan@cdutcm.edu.cn.; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China. zhengchuan@cdutcm.edu.cn.; Sichuan Provincal Engineering Technology Research Center of Natural Small Molecule Drug, Tianfu TCM Innovation Harbour, Chengdu University of Traditional Chinese Medicine, Chengdu, 611930, China. zhengchuan@cdutcm.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101265109%22">Chinese medicine</searchLink> [Chin Med] 2026 Jul 06; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 Jul 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101265109 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1749-8546 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217498546%22">17498546 </searchLink><i>NLM ISO Abbreviation: </i>Chin Med <i>Subsets: </i>PubMed not MEDLINE
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1186/s13020-026-01442-9
    Languages:
      – Code: eng
        Text: English
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      – TitleFull: Shengxian decoction suppresses malignant progression of lung adenocarcinoma by enhancing CD8+ T cell function via the FYN-PI3K/AKT axis.
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            – D: 06
              M: 07
              Text: 2026 Jul 06
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              Y: 2026
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