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The effects of two Leu-to-Pro substitutions, L57P and L43P, on structural and functional properties of cardiac tropomyosin.

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Title: The effects of two Leu-to-Pro substitutions, L57P and L43P, on structural and functional properties of cardiac tropomyosin.
Authors: Lapshina KK; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.; Department of Biophysics, Faculty of Physics, Lomonosov Moscow State University, Russia., Nefedova VV; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia., Kopylova GV; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia., Shchepkin DV; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia., Kochurova AM; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia., Antonets JY; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia., Roman SG; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia., Koubassova NA; Institute of Mechanics, Moscow State University, Russia., Tsaturyan AK; Gray Faculty of Medicine, Tel Aviv University, Israel., Ryabkova NS; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, Russia.; HyTest Ltd., Turku, Finland., Katrukha IA; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, Russia.; HyTest Ltd., Turku, Finland., Kleymenov SY; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.; Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Russia., Ziganshin RH; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia., Bershitsky SY; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia., Matyushenko AM; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia., Levitsky DI; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.
Source: The FEBS journal [FEBS J] 2026 Jul 07. Date of Electronic Publication: 2026 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The effects of two Leu-to-Pro substitutions, L57P and L43P, on structural and functional properties of cardiac tropomyosin.
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  Data: <searchLink fieldCode="AU" term="%22Lapshina+KK%22">Lapshina KK</searchLink>; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.; Department of Biophysics, Faculty of Physics, Lomonosov Moscow State University, Russia.<br /><searchLink fieldCode="AU" term="%22Nefedova+VV%22">Nefedova VV</searchLink>; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Kopylova+GV%22">Kopylova GV</searchLink>; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Shchepkin+DV%22">Shchepkin DV</searchLink>; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Kochurova+AM%22">Kochurova AM</searchLink>; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Antonets+JY%22">Antonets JY</searchLink>; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Roman+SG%22">Roman SG</searchLink>; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Koubassova+NA%22">Koubassova NA</searchLink>; Institute of Mechanics, Moscow State University, Russia.<br /><searchLink fieldCode="AU" term="%22Tsaturyan+AK%22">Tsaturyan AK</searchLink>; Gray Faculty of Medicine, Tel Aviv University, Israel.<br /><searchLink fieldCode="AU" term="%22Ryabkova+NS%22">Ryabkova NS</searchLink>; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, Russia.; HyTest Ltd., Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Katrukha+IA%22">Katrukha IA</searchLink>; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, Russia.; HyTest Ltd., Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Kleymenov+SY%22">Kleymenov SY</searchLink>; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.; Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Ziganshin+RH%22">Ziganshin RH</searchLink>; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Bershitsky+SY%22">Bershitsky SY</searchLink>; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Matyushenko+AM%22">Matyushenko AM</searchLink>; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.<br /><searchLink fieldCode="AU" term="%22Levitsky+DI%22">Levitsky DI</searchLink>; Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Russia.
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              Text: 2026 Jul 07
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