Enhanced Endocytosis and Mitochondrial Stress Underlie Severe Retinitis Pigmentosa With RHO P347L Mutant.
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| Title: | Enhanced Endocytosis and Mitochondrial Stress Underlie Severe Retinitis Pigmentosa With RHO P347L Mutant. |
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| Authors: | Hang C; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Shi X; Department of Pharmaceutical and Artificial-Intelligence Sciences, Institute of Medical Artificial Intelligence, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao T; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Li J; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Zhang T; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Chen Z; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Wu Y; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China., Zhou Y; School of Pharmacy, Ningxia Medical University, Yinchuan, China., Wu S; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Jiao Y; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Wang Y; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Chen H; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Sun J; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China., Li T; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China., Zhang J; Department of Pharmaceutical and Artificial-Intelligence Sciences, Institute of Medical Artificial Intelligence, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Jia H; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China., Wan X; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Li X; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Chen J; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China., Yu B; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China., Sun X; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.; Shanghai Gene Therapy Center, Shanghai, China. |
| Source: | Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2026 Jul 01; Vol. 67 (8), pp. 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42411866 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Enhanced Endocytosis and Mitochondrial Stress Underlie Severe Retinitis Pigmentosa With RHO P347L Mutant. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Hang+C%22">Hang C</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; Department of Pharmaceutical and Artificial-Intelligence Sciences, Institute of Medical Artificial Intelligence, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+T%22">Zhao T</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+T%22">Zhang T</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; School of Pharmacy, Ningxia Medical University, Yinchuan, China.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Jiao+Y%22">Jiao Y</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Pharmaceutical and Artificial-Intelligence Sciences, Institute of Medical Artificial Intelligence, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Jia+H%22">Jia H</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wan+X%22">Wan X</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+X%22">Sun X</searchLink>; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; National Clinical Research Center for Eye Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.; Shanghai Gene Therapy Center, Shanghai, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227703701%22">Investigative ophthalmology & visual science</searchLink> [Invest Ophthalmol Vis Sci] 2026 Jul 01; Vol. 67 (8), pp. 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Association+For+Research+In+Vision+And+Ophthalmology+%28Arvo%29%22">Association For Research In Vision And Ophthalmology (Arvo) </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7703701 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5783 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201460404%22">01460404 </searchLink><i>NLM ISO Abbreviation: </i>Invest Ophthalmol Vis Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42411866 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1167/iovs.67.8.23 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 23 Titles: – TitleFull: Enhanced Endocytosis and Mitochondrial Stress Underlie Severe Retinitis Pigmentosa With RHO P347L Mutant. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hang C – PersonEntity: Name: NameFull: Shi X – PersonEntity: Name: NameFull: Zhao T – PersonEntity: Name: NameFull: Li J – PersonEntity: Name: NameFull: Zhang T – PersonEntity: Name: NameFull: Chen Z – PersonEntity: Name: NameFull: Wu Y – PersonEntity: Name: NameFull: Zhou Y – PersonEntity: Name: NameFull: Wu S – PersonEntity: Name: NameFull: Jiao Y – PersonEntity: Name: NameFull: Wang Y – PersonEntity: Name: NameFull: Chen H – PersonEntity: Name: NameFull: Sun J – PersonEntity: Name: NameFull: Li T – PersonEntity: Name: NameFull: Zhang J – PersonEntity: Name: NameFull: Jia H – PersonEntity: Name: NameFull: Wan X – PersonEntity: Name: NameFull: Li X – PersonEntity: Name: NameFull: Chen J – PersonEntity: Name: NameFull: Yu B – PersonEntity: Name: NameFull: Sun X IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1552-5783 Numbering: – Type: volume Value: 67 – Type: issue Value: 8 Titles: – TitleFull: Investigative ophthalmology & visual science Type: main |
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