Threshold Effects, Cognitive Decline, and Longitudinal Changes in White Matter Hyperintensity Volume.

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Title: Threshold Effects, Cognitive Decline, and Longitudinal Changes in White Matter Hyperintensity Volume.
Authors: Sasannia S; Department of Neurology (S.S., R.L., L.K., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD.; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, MD (S.S., H.-G.S., P.v.Z., L.K.)., Matsyuk M; Neurocritical Care Division, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University Hospital, Baltimore, MD (M.M., P.A.N.)., Wang S; Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD (S.W., J.Z., J.L.P.)., Zhang J; Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD (S.W., J.Z., J.L.P.)., Walker KA; Intramural Research Program, Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD (K.A.W.)., Shin HG; Russell H. Morgan Department of Radiology and Radiological Science (H.-G.S., P.v.Z.)Johns Hopkins University School of Medicine, Baltimore, MD.; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, MD (S.S., H.-G.S., P.v.Z., L.K.)., Leigh R; Department of Neurology (S.S., R.L., L.K., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD., Prince JL; Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD (S.W., J.Z., J.L.P.)., Becker LC; Department of Medicine (L.C.B., L.R.Y., D.V., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD., Yanek LR; Department of Medicine (L.C.B., L.R.Y., D.V., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD., Armstrong NJ; Department of Mathematics and Statistics, Curtin University, Perth, WA, Australia (N.J.A.)., van Zijl P; Russell H. Morgan Department of Radiology and Radiological Science (H.-G.S., P.v.Z.)Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Biomedical Engineering (P.v.Z.)Johns Hopkins University School of Medicine, Baltimore, MD.; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, MD (S.S., H.-G.S., P.v.Z., L.K.)., Vaidya D; Department of Medicine (L.C.B., L.R.Y., D.V., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD., Knutsson L; Department of Neurology (S.S., R.L., L.K., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD.; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, MD (S.S., H.-G.S., P.v.Z., L.K.).; Department of Medical Radiation Physics, Lund University, Sweden (L.K.)., Nyquist PA; Department of Neurology (S.S., R.L., L.K., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Medicine (L.C.B., L.R.Y., D.V., P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Neurosurgery (P.A.N.)Johns Hopkins University School of Medicine, Baltimore, MD.; Neurocritical Care Division, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University Hospital, Baltimore, MD (M.M., P.A.N.).
Source: Stroke [Stroke] 2026 Jul 08. Date of Electronic Publication: 2026 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1524-4628
DOI:10.1161/STROKEAHA.125.054810