Long-lived mammals contain more phosphorylation sites in the SIRT6 C-terminus that enhance PARP1 interaction and resistance to oxidative stress.
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| Title: | Long-lived mammals contain more phosphorylation sites in the SIRT6 C-terminus that enhance PARP1 interaction and resistance to oxidative stress. |
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| Authors: | Gigas J; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; Medical Scientist Training Program, University of Rochester, Rochester, NY, 14627, USA., Meadow ME; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; Medical Scientist Training Program, University of Rochester, Rochester, NY, 14627, USA., Guo J; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Lan C; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Hillpot E; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Martinez JC; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Tombline G; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Bellomio P; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Rivera-Almodóvar V; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Welle KA; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Swovick K; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Hryhorenko JR; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Ablaeva J; Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Ghaemmaghami S; Department of Biology, University of Rochester, Rochester, NY, 14627, USA.; University of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY, 14627, USA., Seluanov A; Department of Biology, University of Rochester, Rochester, NY, 14627, USA. andrei.seluanov@rochester.edu.; Department of Medicine, University of Rochester, Rochester, NY, 14627, USA. andrei.seluanov@rochester.edu., Gorbunova V; Department of Biology, University of Rochester, Rochester, NY, 14627, USA. vera.gorbunova@rochester.edu.; Department of Medicine, University of Rochester, Rochester, NY, 14627, USA. vera.gorbunova@rochester.edu. |
| Source: | GeroScience [Geroscience] 2026 Jul 08. Date of Electronic Publication: 2026 Jul 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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