Complex intervention programme to improve patient safety and facilitate deprescribing in frail older patients living at home (COFRAIL): A process evaluation of a cluster randomised controlled trial.
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| Title: | Complex intervention programme to improve patient safety and facilitate deprescribing in frail older patients living at home (COFRAIL): A process evaluation of a cluster randomised controlled trial. |
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| Authors: | Abraham J; Institute of Health, Midwifery and Nursing Science, Medical Faculty of Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Fleischer S; Institute of Health, Midwifery and Nursing Science, Medical Faculty of Martin Luther University Halle-Wittenberg, Halle (Saale), Germany., Mortsiefer A; Faculty of Health, Department of Medicine, Institute of General Practice and Primary Care, Witten/Herdecke University, Witten, Germany., Drewelow E; Clinic for Forensic Psychiatry, University Medical Centre Rostock, Rostock, Germany., Ritzke M; Institute of General Practice, University Medical Centre Rostock, Rostock, Germany., Wiese B; WG Medical Statistics and IT-Infrastructure, Institute of General Practice, Hannover Medical School, Hannover, Germany., Dintsios CM; Faculty of Medicine, Institute for Health Services Research and Health Economics, Centre for Health and Society, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Bencheva V; Faculty of Health, Center for Clinical Trials, Witten/Herdecke University, Witten, Germany.; Chair of Clinical Pharmacology, Department of Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany., Thürmann P; Chair of Clinical Pharmacology, Department of Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.; Philipp Klee-Institute of Clinical Pharmacology, Helios University Hospital Wuppertal, Wuppertal, Germany., Wilm S; Institute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Meyer G; Institute of Health, Midwifery and Nursing Science, Medical Faculty of Martin Luther University Halle-Wittenberg, Halle (Saale), Germany. |
| Corporate Authors: | COFRAIL study group |
| Source: | PloS one [PLoS One] 2026 Jul 08; Vol. 21 (7), pp. e0350664. Date of Electronic Publication: 2026 Jul 08 (Print Publication: 2026). |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42418407 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Complex intervention programme to improve patient safety and facilitate deprescribing in frail older patients living at home (COFRAIL): A process evaluation of a cluster randomised controlled trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Abraham+J%22">Abraham J</searchLink>; Institute of Health, Midwifery and Nursing Science, Medical Faculty of Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Fleischer+S%22">Fleischer S</searchLink>; Institute of Health, Midwifery and Nursing Science, Medical Faculty of Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Mortsiefer+A%22">Mortsiefer A</searchLink>; Faculty of Health, Department of Medicine, Institute of General Practice and Primary Care, Witten/Herdecke University, Witten, Germany.<br /><searchLink fieldCode="AU" term="%22Drewelow+E%22">Drewelow E</searchLink>; Clinic for Forensic Psychiatry, University Medical Centre Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Ritzke+M%22">Ritzke M</searchLink>; Institute of General Practice, University Medical Centre Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Wiese+B%22">Wiese B</searchLink>; WG Medical Statistics and IT-Infrastructure, Institute of General Practice, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Dintsios+CM%22">Dintsios CM</searchLink>; Faculty of Medicine, Institute for Health Services Research and Health Economics, Centre for Health and Society, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Bencheva+V%22">Bencheva V</searchLink>; Faculty of Health, Center for Clinical Trials, Witten/Herdecke University, Witten, Germany.; Chair of Clinical Pharmacology, Department of Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.<br /><searchLink fieldCode="AU" term="%22Thürmann+P%22">Thürmann P</searchLink>; Chair of Clinical Pharmacology, Department of Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.; Philipp Klee-Institute of Clinical Pharmacology, Helios University Hospital Wuppertal, Wuppertal, Germany.<br /><searchLink fieldCode="AU" term="%22Wilm+S%22">Wilm S</searchLink>; Institute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+G%22">Meyer G</searchLink>; Institute of Health, Midwifery and Nursing Science, Medical Faculty of Martin Luther University Halle-Wittenberg, Halle (Saale), Germany. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22COFRAIL+study+group%22">COFRAIL study group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Jul 08; Vol. 21 (7), pp. e0350664. <i>Date of Electronic Publication: </i>2026 Jul 08 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42418407 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1371/journal.pone.0350664 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0350664 Titles: – TitleFull: Complex intervention programme to improve patient safety and facilitate deprescribing in frail older patients living at home (COFRAIL): A process evaluation of a cluster randomised controlled trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Abraham J – PersonEntity: Name: NameFull: Fleischer S – PersonEntity: Name: NameFull: Mortsiefer A – PersonEntity: Name: NameFull: Drewelow E – PersonEntity: Name: NameFull: Ritzke M – PersonEntity: Name: NameFull: Wiese B – PersonEntity: Name: NameFull: Dintsios CM – PersonEntity: Name: NameFull: Bencheva V – PersonEntity: Name: NameFull: Thürmann P – PersonEntity: Name: NameFull: Wilm S – PersonEntity: Name: NameFull: Meyer G IsPartOfRelationships: – BibEntity: Dates: – D: 08 M: 07 Text: 2026 Jul 08 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1932-6203 Numbering: – Type: volume Value: 21 – Type: issue Value: 7 Titles: – TitleFull: PloS one Type: main |
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