Humans and rhesus macaques share maturation pathways of HIV-1 envelope-reactive V3-glycan bnAb lineages.

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Title: Humans and rhesus macaques share maturation pathways of HIV-1 envelope-reactive V3-glycan bnAb lineages.
Authors: Clark M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Li H; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Martin M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Evangelous TD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Gobeil SM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Berry M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Wagh K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.; New Mexico Consortium, Los Alamos, NM 87544, USA., Giorgi EE; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.; New Mexico Consortium, Los Alamos, NM 87544, USA., Hogarty MP; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Zhao C; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Wang S; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Marchitto L; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Ding W; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Park Y; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Rando J; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Carey J; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Connell AJ; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Skelly AN; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Chen Y; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Rohr S; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Balgobin S; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Jiang C; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Venkatayogi S; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Mansouri K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Lindenberger J; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Hora B; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Doria-Rose N; Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA., Mascola J; Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA., van Gils MJ; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands., Sanders RW; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC University of Amsterdam, Amsterdam, Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, Netherlands.; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA., Korber B; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.; New Mexico Consortium, Los Alamos, NM 87544, USA., Hahn B; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Acharya P; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA., Wiehe K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Shaw GM; Departments of Medicine and Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Williams WB; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Jul 08; Vol. 18 (857), pp. eaee9864. Date of Electronic Publication: 2026 Jul 08.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.aee9864