Preactivated macrophage membrane vesicle-engineered yolk-shell nanoplatform for dual-targeted mild photothermal-triggered cascade gas therapy in MRSA-infected bone and soft tissue regeneration.

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Title: Preactivated macrophage membrane vesicle-engineered yolk-shell nanoplatform for dual-targeted mild photothermal-triggered cascade gas therapy in MRSA-infected bone and soft tissue regeneration.
Authors: Su JW; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China., Lin LL; Department of Pathophysiology & Hubei Province Key Laboratory of Allergy and Immunology, Taikang Medical School (School of Basic Medical Sciences), Wuhan University, Wuhan, 430071, China., Lv XD; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China., Xu ZH; Department of Pathology, School of Basic Medical Science, Xi'an Medical University, Xi'an, 710021, China., Qu WQ; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China., Peng HH; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China., Yang M; Department of Orthopedics, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, 434021, China., Zhou K; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China., Zhao YC; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China., Zhao Y; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. Electronic address: mocuishle123@163.com., Gu HY; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. Electronic address: 2018283030143@whu.edu.cn., Yu AX; Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. Electronic address: yuaixi@whu.edu.cn.
Source: Biomaterials [Biomaterials] 2026 Jul 07; Vol. 336, pp. 124416. Date of Electronic Publication: 2026 Jul 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1878-5905
DOI:10.1016/j.biomaterials.2026.124416