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Glycolysis-enhancing α1-adrenergic antagonists have therapeutic potential in Alzheimer's disease.

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Title: Glycolysis-enhancing α1-adrenergic antagonists have therapeutic potential in Alzheimer's disease.
Authors: Zhang Q; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA. Qiang-zhang@uiowa.edu., Schultz JL; Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA., Simmering JE; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA., Kirkpatrick BQ; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA., Weber MA; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA., Skuodas S; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA., Hicks T; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA., Pierce G; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA., Laughlin M; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA., George B; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA., Bertolli AX; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA., Larson T; Duke Medical Scientist Training Program, Department of Neurobiology, Duke University, Durham, NC, 27710, USA., Thangavel R; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA., Oya M; Johns Hopkins University, Baltimore, MD, 21205, USA., Meyerholz DK; Department of Pathology, University of Iowa, Iowa City, IA, 52242, USA., Aldridge G; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA., Fassler J; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA., Narayanan NS; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA. Nandakumar-narayanan@uiowa.edu.
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 Jul 09. Date of Electronic Publication: 2026 Jul 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glycolysis-enhancing α<subscript>1</subscript>-adrenergic antagonists have therapeutic potential in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA. Qiang-zhang@uiowa.edu.<br /><searchLink fieldCode="AU" term="%22Schultz+JL%22">Schultz JL</searchLink>; Department of Psychiatry, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Simmering+JE%22">Simmering JE</searchLink>; Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Kirkpatrick+BQ%22">Kirkpatrick BQ</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Weber+MA%22">Weber MA</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Skuodas+S%22">Skuodas S</searchLink>; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Hicks+T%22">Hicks T</searchLink>; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Pierce+G%22">Pierce G</searchLink>; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Laughlin+M%22">Laughlin M</searchLink>; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22George+B%22">George B</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Bertolli+AX%22">Bertolli AX</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Larson+T%22">Larson T</searchLink>; Duke Medical Scientist Training Program, Department of Neurobiology, Duke University, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Thangavel+R%22">Thangavel R</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Oya+M%22">Oya M</searchLink>; Johns Hopkins University, Baltimore, MD, 21205, USA.<br /><searchLink fieldCode="AU" term="%22Meyerholz+DK%22">Meyerholz DK</searchLink>; Department of Pathology, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Aldridge+G%22">Aldridge G</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Fassler+J%22">Fassler J</searchLink>; Department of Biology, University of Iowa, Iowa City, IA, 52242, USA.<br /><searchLink fieldCode="AU" term="%22Narayanan+NS%22">Narayanan NS</searchLink>; Department of Neurology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, 169 Newton Road, Iowa City, IA, 52242, USA. Nandakumar-narayanan@uiowa.edu.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101511643 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-9193 (Electronic) <i>NLM ISO Abbreviation: </i>Alzheimers Res Ther <i>Subsets: </i>MEDLINE
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