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Rapamycin Partially Reverts Cavernoma Endothelial Cell Phenotype and, When Combined With Lapatinib, Ameliorates Chronic Lesions.

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Title: Rapamycin Partially Reverts Cavernoma Endothelial Cell Phenotype and, When Combined With Lapatinib, Ameliorates Chronic Lesions.
Authors: García-Colomer M; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Martínez JE; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Díaz-Gómez L; Department of Pharmacology, Pharmacy, and Pharmaceutical Technology, Instituto De Materiales (iMATUS), and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela, Santiago de Compostela, A Coruña, Spain., Sartages M; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Esquinas-Román EM; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Riobello C; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Martínez-Delgado D; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., González-Pérez D; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Gómez-Durán A; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Fidalgo M; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Varela-Rey M; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Pombo CM; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Zalvide J; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2026 Jul; Vol. 30 (13), pp. e71280.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1582-4934
DOI:10.1111/jcmm.71280