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Rapamycin Partially Reverts Cavernoma Endothelial Cell Phenotype and, When Combined With Lapatinib, Ameliorates Chronic Lesions.

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Title: Rapamycin Partially Reverts Cavernoma Endothelial Cell Phenotype and, When Combined With Lapatinib, Ameliorates Chronic Lesions.
Authors: García-Colomer M; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Martínez JE; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Díaz-Gómez L; Department of Pharmacology, Pharmacy, and Pharmaceutical Technology, Instituto De Materiales (iMATUS), and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela, Santiago de Compostela, A Coruña, Spain., Sartages M; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Esquinas-Román EM; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Riobello C; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Martínez-Delgado D; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., González-Pérez D; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Gómez-Durán A; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Fidalgo M; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Varela-Rey M; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain., Pombo CM; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain., Zalvide J; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.
Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2026 Jul; Vol. 30 (13), pp. e71280.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rapamycin Partially Reverts Cavernoma Endothelial Cell Phenotype and, When Combined With Lapatinib, Ameliorates Chronic Lesions.
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  Data: <searchLink fieldCode="AU" term="%22García-Colomer+M%22">García-Colomer M</searchLink>; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Martínez+JE%22">Martínez JE</searchLink>; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Díaz-Gómez+L%22">Díaz-Gómez L</searchLink>; Department of Pharmacology, Pharmacy, and Pharmaceutical Technology, Instituto De Materiales (iMATUS), and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela, Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Sartages+M%22">Sartages M</searchLink>; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Esquinas-Román+EM%22">Esquinas-Román EM</searchLink>; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Riobello+C%22">Riobello C</searchLink>; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Martínez-Delgado+D%22">Martínez-Delgado D</searchLink>; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22González-Pérez+D%22">González-Pérez D</searchLink>; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez-Durán+A%22">Gómez-Durán A</searchLink>; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Fidalgo+M%22">Fidalgo M</searchLink>; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Varela-Rey+M%22">Varela-Rey M</searchLink>; Department of Biochemistry and Molecular Biology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade de Santiago de Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Pombo+CM%22">Pombo CM</searchLink>; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Zalvide+J%22">Zalvide J</searchLink>; Department of Physiology, Centro Singular De Medicina Molecular E Enfermedades Crónicas (CiMUS) and Instituto Sanitario De Santiago De Compostela (IDIS), Universidade De Santiago De Compostela (USC), Santiago de Compostela, A Coruña, Spain.
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        Value: 10.1111/jcmm.71280
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      – TitleFull: Rapamycin Partially Reverts Cavernoma Endothelial Cell Phenotype and, When Combined With Lapatinib, Ameliorates Chronic Lesions.
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