Clade-3 Bat Sarbecovirus PRD0038 Reveals Constraints on Coronavirus Emergence and Immune Sensitivity.

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Title: Clade-3 Bat Sarbecovirus PRD0038 Reveals Constraints on Coronavirus Emergence and Immune Sensitivity.
Authors: Abdelgadir A; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Kong EF; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Parsons RJ; Duke Human Vaccine Institute, Durham, NC, USA.; Duke University, Department of Biochemistry, Durham, NC, USA., Mallory ML; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Yount BL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Scobey T; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Powers JM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gully KL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Adams LE; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Edwards RJ; Duke Human Vaccine Institute, Durham, NC, USA.; Duke University, Department of Medicine, Durham, NC, USA., Mansouri K; Duke Human Vaccine Institute, Durham, NC, USA., Devkota P; Duke Human Vaccine Institute, Durham, NC, USA., Janowska K; Duke Human Vaccine Institute, Durham, NC, USA., Pathirage R; Duke Human Vaccine Institute, Durham, NC, USA., Catanzaro NJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Biggers AL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Lavinder JJ; Department of Chemical Engineering, The University of Texas at Austin, Austin, TX, USA., Ippolito GC; Texas Biomedical Research Institute, San Antonio, TX, USA., Heise MT; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Acharya P; Duke Human Vaccine Institute, Durham, NC, USA.; Duke University, Department of Biochemistry, Durham, NC, USA.; Duke University, Department of Surgery, Durham, NC, USA., Gralinski LE; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Baric RS; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Source: Research square [Res Sq] 2026 Jul 02. Date of Electronic Publication: 2026 Jul 02.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2693-5015
DOI:10.21203/rs.3.rs-9954172/v1