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Systemic Inflammation as a Modulator of FcRn-dependent IgG Pharmacokinetics: Implications for Broadly Neutralising Antibody Efficacy in HIV Prevention.

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Title: Systemic Inflammation as a Modulator of FcRn-dependent IgG Pharmacokinetics: Implications for Broadly Neutralising Antibody Efficacy in HIV Prevention.
Authors: Khumalo A; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, 4001, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, 4001, South Africa., Pillay S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, 4001, South Africa., Mohan J; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, 4001, South Africa., Mahomed S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, 4001, South Africa.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, 4001, South Africa., Archary D; Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, 4001, South Africa. Desh.Archary@caprisa.org.; Department of Medical Microbiology, University of KwaZulu-Natal, Durban, 4001, South Africa. Desh.Archary@caprisa.org.
Source: Current HIV/AIDS reports [Curr HIV/AIDS Rep] 2026 Jul 10; Vol. 23 (1). Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article; Review
Journal Info: Publisher: Current Science Country of Publication: United States NLM ID: 101235661 Publication Model: Electronic Cited Medium: Internet ISSN: 1548-3576 (Electronic) Linking ISSN: 15483568 NLM ISO Abbreviation: Curr HIV/AIDS Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1548-3576
DOI:10.1007/s11904-026-00791-2