Topical medium-length PDRN enhances dermal extracellular matrix repair in photodamaged skin via PI3K-Akt/TGF-β-regulated pathways.
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| Title: | Topical medium-length PDRN enhances dermal extracellular matrix repair in photodamaged skin via PI3K-Akt/TGF-β-regulated pathways. |
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| Authors: | Ye R; Department of Dermatology & Venereology, Center of Cosmetic Safety and Efficacy Evaluation and NMPA Key Laboratory for Human Evaluation and Big Data of Cosmetics, West China Hospital, Sichuan University, Chengdu, China.; UNISKIN Research Institute on Skin Aging, Inertia Shanghai Biotechnology Co., Ltd., Shanghai, China.; DermaHealth Shanghai Biotechnology Co., Ltd., Shanghai, China., Wang Q; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China., Du L; UNISKIN Research Institute on Skin Aging, Inertia Shanghai Biotechnology Co., Ltd., Shanghai, China.; DermaHealth Shanghai Biotechnology Co., Ltd., Shanghai, China., Li L; Department of Dermatology & Venereology, Center of Cosmetic Safety and Efficacy Evaluation and NMPA Key Laboratory for Human Evaluation and Big Data of Cosmetics, West China Hospital, Sichuan University, Chengdu, China., Hu F; UNISKIN Research Institute on Skin Aging, Inertia Shanghai Biotechnology Co., Ltd., Shanghai, China.; DermaHealth Shanghai Biotechnology Co., Ltd., Shanghai, China. |
| Source: | PloS one [PLoS One] 2026 Jul 10; Vol. 21 (7), pp. e0350905. Date of Electronic Publication: 2026 Jul 10 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0350905 |