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Infection of Rhesus Macaques with O'nyong-nyong virus UVRI-0804 recapitulates key aspects of human clinical disease.

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Title: Infection of Rhesus Macaques with O'nyong-nyong virus UVRI-0804 recapitulates key aspects of human clinical disease.
Authors: Jaeger HK; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Denton M; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Andoh TF; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Kreklywich CN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Gao L; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.; Biostatistics Shared Resources, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, United States of America., Pung LJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Streblow ZJ; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., McMonigal A; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.; Biostatistics Shared Resources, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, United States of America., Ray K; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America., Graves B; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Streblow MM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America., Barber-Axthelm AM; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America., Zilverberg G; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America., Terry M; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America., Fei SS; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America., Hogan G; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Schultz DC; Department of Biochemistry & Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Cherry S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Axthelm MK; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America., Labriola CS; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America., Heise MT; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America., Streblow DN; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2026 Jul 10; Vol. 20 (7), pp. e0013780. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE
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  Data: Infection of Rhesus Macaques with O'nyong-nyong virus UVRI-0804 recapitulates key aspects of human clinical disease.
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  Data: <searchLink fieldCode="AU" term="%22Jaeger+HK%22">Jaeger HK</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Denton+M%22">Denton M</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Andoh+TF%22">Andoh TF</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Kreklywich+CN%22">Kreklywich CN</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.; Biostatistics Shared Resources, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Pung+LJ%22">Pung LJ</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Streblow+ZJ%22">Streblow ZJ</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22McMonigal+A%22">McMonigal A</searchLink>; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.; Biostatistics Shared Resources, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Ray+K%22">Ray K</searchLink>; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Graves+B%22">Graves B</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Streblow+MM%22">Streblow MM</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Barber-Axthelm+AM%22">Barber-Axthelm AM</searchLink>; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Zilverberg+G%22">Zilverberg G</searchLink>; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Terry+M%22">Terry M</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Fei+SS%22">Fei SS</searchLink>; Bioinformatics & Biostatistics Core, Oregon National Primate Research Center, Oregon Health & Science University, Portland, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Hogan+G%22">Hogan G</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Schultz+DC%22">Schultz DC</searchLink>; Department of Biochemistry & Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Cherry+S%22">Cherry S</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Axthelm+MK%22">Axthelm MK</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Labriola+CS%22">Labriola CS</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.<br /><searchLink fieldCode="AU" term="%22Heise+MT%22">Heise MT</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Streblow+DN%22">Streblow DN</searchLink>; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, United States of America.; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Beaverton, Oregon, United States of America.
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