Mitochondrial translocation of DNMT3L suppresses oxidative phosphorylation and restrains megakaryopoiesis.

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Title: Mitochondrial translocation of DNMT3L suppresses oxidative phosphorylation and restrains megakaryopoiesis.
Authors: Chen SW; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Chen HW; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Chu CH; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Hsu PS; Institute of Biotechnology, National Taiwan University, Taipei City, Taiwan., Yu YS; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Lin SP; Institute of Biotechnology, National Taiwan University, Taipei City, Taiwan; Genome and Systems Biology Degree Program, National Taiwan University/Academia Sinica, Taipei City, Taiwan; Agricultural Biotechnology Research Center, Academia Sinica, Taipei City, Taiwan; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei City, Taiwan., Wu YX; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Lin EC; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA., Lin TA; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan; Division of Hematology & Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan., Chen MH; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Chang HY; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Yang HY; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan., Lee HC; Department and Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan; Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei City, Taiwan; Department of Medical Research, Taipei Veterans General Hospital, Taipei City, Taiwan., Chang YI; Department and Institute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan; Stem Cell Research Center, College of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan. Electronic address: ychang@nycu.edu.tw.
Source: Mitochondrion [Mitochondrion] 2026 Jul 10; Vol. 91, pp. 102192. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100968751 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8278 (Electronic) Linking ISSN: 15677249 NLM ISO Abbreviation: Mitochondrion Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-8278
DOI:10.1016/j.mito.2026.102192