Age-independent immune subtypes in type 1 diabetes exhibit distinct post-onset progression rates and immunotherapeutic responses.

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Title: Age-independent immune subtypes in type 1 diabetes exhibit distinct post-onset progression rates and immunotherapeutic responses.
Authors: Bedrat A; The Max McGee Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA.; Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA., Truchan NA; The Max McGee Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA.; Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA., Pant T; The Max McGee Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA.; Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA., Jia S; The Max McGee Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA.; Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA., Roethle MF; The Max McGee Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA.; Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA., Chen YG; The Max McGee Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA.; Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA., Lin CW; Division of Biostatistics, Data Science Institute, The Medical College of Wisconsin, Milwaukee, WI, USA., Hessner MJ; The Max McGee Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA. mhessner@mcw.edu.; Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA. mhessner@mcw.edu.
Source: Diabetologia [Diabetologia] 2026 Jul 11. Date of Electronic Publication: 2026 Jul 11.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-0428
DOI:10.1007/s00125-026-06794-3