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NME3 promotes clear cell renal cell carcinoma progression and modulates TKI response through MFN1/2-dependent mitochondrial fusion and mitophagy suppression.

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Title: NME3 promotes clear cell renal cell carcinoma progression and modulates TKI response through MFN1/2-dependent mitochondrial fusion and mitophagy suppression.
Authors: Cao S; School of Medicine, Nankai University, Tianjin, China.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Chen X; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China., Zhang C; School of Medicine, Nankai University, Tianjin, China.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Feng Y; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China., Shi C; School of Medicine, Nankai University, Tianjin, China.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Wang J; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China., Xu Q; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China., Huang X; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China., Ma X; School of Medicine, Nankai University, Tianjin, China. mxin301@126.com.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. mxin301@126.com., Fan W; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. fan_wenmei@163.com.
Source: Oncogene [Oncogene] 2026 Jul 10. Date of Electronic Publication: 2026 Jul 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: NME3 promotes clear cell renal cell carcinoma progression and modulates TKI response through MFN1/2-dependent mitochondrial fusion and mitophagy suppression.
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  Data: <searchLink fieldCode="AU" term="%22Cao+S%22">Cao S</searchLink>; School of Medicine, Nankai University, Tianjin, China.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; School of Medicine, Nankai University, Tianjin, China.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Shi+C%22">Shi C</searchLink>; School of Medicine, Nankai University, Tianjin, China.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Xu+Q%22">Xu Q</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.; Medical School of Chinese PLA, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; School of Medicine, Nankai University, Tianjin, China. mxin301@126.com.; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. mxin301@126.com.<br /><searchLink fieldCode="AU" term="%22Fan+W%22">Fan W</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. fan_wenmei@163.com.
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  Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Jul 10. <i>Date of Electronic Publication: </i>2026 Jul 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8711562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209509232%22">09509232 </searchLink><i>NLM ISO Abbreviation: </i>Oncogene <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41388-026-03892-9
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      – Code: eng
        Text: English
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      – TitleFull: NME3 promotes clear cell renal cell carcinoma progression and modulates TKI response through MFN1/2-dependent mitochondrial fusion and mitophagy suppression.
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            NameFull: Chen X
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            – D: 10
              M: 07
              Text: 2026 Jul 10
              Type: published
              Y: 2026
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