Safety and preliminary efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation in hereditary cerebellar ataxia: phase I/IIa clinical trial.
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| Title: | Safety and preliminary efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation in hereditary cerebellar ataxia: phase I/IIa clinical trial. |
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| Authors: | Moghaddam AS; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Tavakol-Afshari J; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Farkhad NK; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Mojarrad M; Department of Medical Genetics and Molecular Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Eslami M; Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.; International Faculty, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.; Department of Genetics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Savad S; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Khodadoust MA; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Orafaie A; Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran., Sobhani M; Department of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Farmanbar A; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Dashtkoohi M; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany., Khodayari H; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany., Hassani D; Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran., Najafi S; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Najafi P; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Hescheler J; European Center for Personalized Medicine, Medical Center, European Cell Medicine Institute, Düsseldorf, Germany., Nayernia K; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany. Nayernia@icpm.center., Boroumand A; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. arboroumand.ab@gmail.com.; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany. arboroumand.ab@gmail.com. |
| Source: | Stem cell research & therapy [Stem Cell Res Ther] 2026 Jul 10; Vol. 17 (1). Date of Electronic Publication: 2026 Jul 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42432710 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Safety and preliminary efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation in hereditary cerebellar ataxia: phase I/IIa clinical trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Moghaddam+AS%22">Moghaddam AS</searchLink>; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Tavakol-Afshari+J%22">Tavakol-Afshari J</searchLink>; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Farkhad+NK%22">Farkhad NK</searchLink>; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Mojarrad+M%22">Mojarrad M</searchLink>; Department of Medical Genetics and Molecular Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Eslami+M%22">Eslami M</searchLink>; Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.; International Faculty, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.; Department of Genetics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Savad+S%22">Savad S</searchLink>; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Khodadoust+MA%22">Khodadoust MA</searchLink>; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Orafaie+A%22">Orafaie A</searchLink>; Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Sobhani+M%22">Sobhani M</searchLink>; Department of Neurology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Farmanbar+A%22">Farmanbar A</searchLink>; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Dashtkoohi+M%22">Dashtkoohi M</searchLink>; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Khodayari+H%22">Khodayari H</searchLink>; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Hassani+D%22">Hassani D</searchLink>; Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Najafi+S%22">Najafi S</searchLink>; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Najafi+P%22">Najafi P</searchLink>; Neuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.<br /><searchLink fieldCode="AU" term="%22Hescheler+J%22">Hescheler J</searchLink>; European Center for Personalized Medicine, Medical Center, European Cell Medicine Institute, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Nayernia+K%22">Nayernia K</searchLink>; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany. Nayernia@icpm.center.<br /><searchLink fieldCode="AU" term="%22Boroumand+A%22">Boroumand A</searchLink>; Immunology Research Center, Department of Immunology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. arboroumand.ab@gmail.com.; International Center for Personalized Medicine (P7Medicine), 40235, Düsseldorf, Germany. arboroumand.ab@gmail.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101527581%22">Stem cell research & therapy</searchLink> [Stem Cell Res Ther] 2026 Jul 10; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Jul 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101527581 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-6512 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217576512%22">17576512 </searchLink><i>NLM ISO Abbreviation: </i>Stem Cell Res Ther <i>Subsets: </i>MEDLINE; In Process |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42432710 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13287-026-05163-6 Languages: – Code: eng Text: English Titles: – TitleFull: Safety and preliminary efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation in hereditary cerebellar ataxia: phase I/IIa clinical trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Moghaddam AS – PersonEntity: Name: NameFull: Tavakol-Afshari J – PersonEntity: Name: NameFull: Farkhad NK – PersonEntity: Name: NameFull: Mojarrad M – PersonEntity: Name: NameFull: Eslami M – PersonEntity: Name: NameFull: Savad S – PersonEntity: Name: NameFull: Khodadoust MA – PersonEntity: Name: NameFull: Orafaie A – PersonEntity: Name: NameFull: Sobhani M – PersonEntity: Name: NameFull: Farmanbar A – PersonEntity: Name: NameFull: Dashtkoohi M – PersonEntity: Name: NameFull: Khodayari H – PersonEntity: Name: NameFull: Hassani D – PersonEntity: Name: NameFull: Najafi S – PersonEntity: Name: NameFull: Najafi P – PersonEntity: Name: NameFull: Hescheler J – PersonEntity: Name: NameFull: Nayernia K – PersonEntity: Name: NameFull: Boroumand A IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 07 Text: 2026 Jul 10 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1757-6512 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: Stem cell research & therapy Type: main |
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