View in EDS

Integrated deep learning and multi-scale modeling for the discovery of pan-genotypic HCV NS5B polymerase inhibitors.

Saved in:
Bibliographic Details
Title: Integrated deep learning and multi-scale modeling for the discovery of pan-genotypic HCV NS5B polymerase inhibitors.
Authors: Han D; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China. hd@xxmu.edu.cn.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China. hd@xxmu.edu.cn.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China. hd@xxmu.edu.cn., Liu F; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Peng X; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Wang Y; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Shi Z; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Xue Y; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Yang H; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Wang M; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Lu J; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Liu T; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China., Cui S; School of Forensic, Henan Medical University, Xinxiang, 453003, Henan, China., Xu Y; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China. yxu@xxmu.edu.cn.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China. yxu@xxmu.edu.cn.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China. yxu@xxmu.edu.cn.
Source: Molecular diversity [Mol Divers] 2026 Jul 11. Date of Electronic Publication: 2026 Jul 11.
Publication Type: Journal Article
Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42435189
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Integrated deep learning and multi-scale modeling for the discovery of pan-genotypic HCV NS5B polymerase inhibitors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Han+D%22">Han D</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China. hd@xxmu.edu.cn.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China. hd@xxmu.edu.cn.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China. hd@xxmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+F%22">Liu F</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Peng+X%22">Peng X</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Shi+Z%22">Shi Z</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Xue+Y%22">Xue Y</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Cui+S%22">Cui S</searchLink>; School of Forensic, Henan Medical University, Xinxiang, 453003, Henan, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; School of Medical Engineering, Henan Medical University, Xinxiang, 453003, Henan, China. yxu@xxmu.edu.cn.; Henan International Joint Laboratory of Neural Information Analysis and Drug Intelligent Design, Xinxiang, 453003, Henan, China. yxu@xxmu.edu.cn.; Xinxiang Key Laboratory of Biomedical Information Research, Xinxiang, 453003, Henan, China. yxu@xxmu.edu.cn.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229516534%22">Molecular diversity</searchLink> [Mol Divers] 2026 Jul 11. <i>Date of Electronic Publication: </i>2026 Jul 11.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22ESCOM+Science+Publishers%22">ESCOM Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9516534 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-501X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213811991%22">13811991 </searchLink><i>NLM ISO Abbreviation: </i>Mol Divers <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42435189
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s11030-026-11633-z
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Integrated deep learning and multi-scale modeling for the discovery of pan-genotypic HCV NS5B polymerase inhibitors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Han D
      – PersonEntity:
          Name:
            NameFull: Liu F
      – PersonEntity:
          Name:
            NameFull: Peng X
      – PersonEntity:
          Name:
            NameFull: Wang Y
      – PersonEntity:
          Name:
            NameFull: Shi Z
      – PersonEntity:
          Name:
            NameFull: Xue Y
      – PersonEntity:
          Name:
            NameFull: Yang H
      – PersonEntity:
          Name:
            NameFull: Wang M
      – PersonEntity:
          Name:
            NameFull: Lu J
      – PersonEntity:
          Name:
            NameFull: Liu T
      – PersonEntity:
          Name:
            NameFull: Cui S
      – PersonEntity:
          Name:
            NameFull: Xu Y
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 11
              M: 07
              Text: 2026 Jul 11
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1573-501X
          Titles:
            – TitleFull: Molecular diversity
              Type: main
ResultId 1