Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.

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Title: Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.
Authors: Johnson CR; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Gillette L; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Qurbonov Q; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Plone A; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Schmieder SS; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Anderson M; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Cibelli K; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Zhang YJ; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.; Center for Microbiome Therapeutics and Informatics, Massachusetts Institute of Technology, Cambridge, MA, United States., Raghunathan K; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Field M; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Goyal A; Department of Pediatric Gastroenterology, Hepatology and Nutrition, Stanford University, Stanford, CA, United States., Kahn SA; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Snapper SB; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Silvester JA; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States., Thiagarajah JR; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.; Harvard Digestive Disease Center, Harvard Medical School, Boston, MA, United States.; Congenital Enteropathy Program, Boston Children's Hospital, Boston, MA, United States.
Source: Inflammatory bowel diseases [Inflamm Bowel Dis] 2026 Jul 11. Date of Electronic Publication: 2026 Jul 11.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9508162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-4844 (Electronic) Linking ISSN: 10780998 NLM ISO Abbreviation: Inflamm Bowel Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.
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  Data: <searchLink fieldCode="AU" term="%22Johnson+CR%22">Johnson CR</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Gillette+L%22">Gillette L</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Qurbonov+Q%22">Qurbonov Q</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Plone+A%22">Plone A</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Schmieder+SS%22">Schmieder SS</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Anderson+M%22">Anderson M</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Cibelli+K%22">Cibelli K</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+YJ%22">Zhang YJ</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.; Center for Microbiome Therapeutics and Informatics, Massachusetts Institute of Technology, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Raghunathan+K%22">Raghunathan K</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Field+M%22">Field M</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Goyal+A%22">Goyal A</searchLink>; Department of Pediatric Gastroenterology, Hepatology and Nutrition, Stanford University, Stanford, CA, United States.<br /><searchLink fieldCode="AU" term="%22Kahn+SA%22">Kahn SA</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Snapper+SB%22">Snapper SB</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Silvester+JA%22">Silvester JA</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Thiagarajah+JR%22">Thiagarajah JR</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.; Harvard Digestive Disease Center, Harvard Medical School, Boston, MA, United States.; Congenital Enteropathy Program, Boston Children's Hospital, Boston, MA, United States.
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        Value: 10.1093/ibd/izag137
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        Text: English
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              Text: 2026 Jul 11
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