Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid-Induced Bone Loss.
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| Title: | Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid-Induced Bone Loss. |
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| Authors: | Han LJ; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Miao JS; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Shi YF; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.; Department of Orthopedics, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China., Tu YT; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Lin YZ; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Chen LJ; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Lin BH; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Li HL; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Zheng XQ; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Wu HQ; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Liu HX; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Yang L; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Wu AM; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Lin Z; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.; Department of Plastic and Aesthetic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China., Xiao J; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Zheng G; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China., Jin C; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China. |
| Source: | Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Jul 13, pp. e76586. Date of Electronic Publication: 2026 Jul 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42439361 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid-Induced Bone Loss. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Han+LJ%22">Han LJ</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Miao+JS%22">Miao JS</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Shi+YF%22">Shi YF</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.; Department of Orthopedics, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Tu+YT%22">Tu YT</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Lin+YZ%22">Lin YZ</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+LJ%22">Chen LJ</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Lin+BH%22">Lin BH</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+HL%22">Li HL</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zheng+XQ%22">Zheng XQ</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Wu+HQ%22">Wu HQ</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Liu+HX%22">Liu HX</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Wu+AM%22">Wu AM</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.; Department of Plastic and Aesthetic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Xiao+J%22">Xiao J</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Zheng+G%22">Zheng G</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Jin+C%22">Jin C</searchLink>; Key Laboratory of Orthopaedics of Zhejiang Province, Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Key Laboratory of Osteoporosis and Geriatric Bone Health of Wenzhou, Wenzhou, Zhejiang, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101664569%22">Advanced science (Weinheim, Baden-Wurttemberg, Germany)</searchLink> [Adv Sci (Weinh)] 2026 Jul 13, pp. e76586. <i>Date of Electronic Publication: </i>2026 Jul 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22WILEY-VCH%22">WILEY-VCH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101664569 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2198-3844 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221983844%22">21983844 </searchLink><i>NLM ISO Abbreviation: </i>Adv Sci (Weinh) <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/advs.76586 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e76586 Titles: – TitleFull: Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid-Induced Bone Loss. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Han LJ – PersonEntity: Name: NameFull: Miao JS – PersonEntity: Name: NameFull: Shi YF – PersonEntity: Name: NameFull: Tu YT – PersonEntity: Name: NameFull: Lin YZ – PersonEntity: Name: NameFull: Chen LJ – PersonEntity: Name: NameFull: Lin BH – PersonEntity: Name: NameFull: Li HL – PersonEntity: Name: NameFull: Zheng XQ – PersonEntity: Name: NameFull: Wu HQ – PersonEntity: Name: NameFull: Liu HX – PersonEntity: Name: NameFull: Yang L – PersonEntity: Name: NameFull: Wu AM – PersonEntity: Name: NameFull: Lin Z – PersonEntity: Name: NameFull: Xiao J – PersonEntity: Name: NameFull: Zheng G – PersonEntity: Name: NameFull: Jin C IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 07 Text: 2026 Jul 13 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2198-3844 Titles: – TitleFull: Advanced science (Weinheim, Baden-Wurttemberg, Germany) Type: main |
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