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Synergistic integration of μ-SPE and ammoniated adduct-based MRM for sensitive UPLC-MS/MS quantification of PEG1000: a comparative study against in-source CID and application to zebrafish tissue distribution.

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Title: Synergistic integration of μ-SPE and ammoniated adduct-based MRM for sensitive UPLC-MS/MS quantification of PEG1000: a comparative study against in-source CID and application to zebrafish tissue distribution.
Authors: Zhou X; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Duan S; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Lou Y; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Deng Y; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Feng S; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Liu J; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Zhang J; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China., Xi Y; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China., Shi M; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China. shimy@dlut.edu.cn.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China. shimy@dlut.edu.cn., Yin L; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China. leiyin@dlut.edu.cn.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China. leiyin@dlut.edu.cn.
Source: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2026 Jul 13. Date of Electronic Publication: 2026 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-2650 (Electronic) Linking ISSN: 16182642 NLM ISO Abbreviation: Anal Bioanal Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synergistic integration of μ-SPE and ammoniated adduct-based MRM for sensitive UPLC-MS/MS quantification of PEG1000: a comparative study against in-source CID and application to zebrafish tissue distribution.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+X%22">Zhou X</searchLink>; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China.<br /><searchLink fieldCode="AU" term="%22Duan+S%22">Duan S</searchLink>; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China.<br /><searchLink fieldCode="AU" term="%22Lou+Y%22">Lou Y</searchLink>; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China.<br /><searchLink fieldCode="AU" term="%22Deng+Y%22">Deng Y</searchLink>; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China.<br /><searchLink fieldCode="AU" term="%22Feng+S%22">Feng S</searchLink>; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China.<br /><searchLink fieldCode="AU" term="%22Xi+Y%22">Xi Y</searchLink>; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China.<br /><searchLink fieldCode="AU" term="%22Shi+M%22">Shi M</searchLink>; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China. shimy@dlut.edu.cn.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China. shimy@dlut.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yin+L%22">Yin L</searchLink>; Central Hospital of Dalian University of Technology, Dalian University of Technology, Dalian, Liaoning, 116023, P.R. China. leiyin@dlut.edu.cn.; School of Chemical Engineering, Ocean and Life Sciences, Dalian University of Technology, NO.2 Dagong Road, New District of Liaodong Bay, Panjin, 124221, P.R. China. leiyin@dlut.edu.cn.
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              Text: 2026 Jul 13
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