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Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

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Title: Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
Authors: Blazhenets G; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco., Soleimani-Meigooni DN; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, California., Chiotis K; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.; Center for Alzheimer Research, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Allen IE; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco., Rabinovici GD; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.; Department of Radiology and Biomedical Imaging, University of California, San Francisco., La Joie R; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco., Apostolova LG; Indiana University School of Medicine, Indianapolis., Asken BM; Department of Clinical and Health Psychology, 1Florida Alzheimer's Disease Research Center, University of Florida, Gainesville., Bejanin A; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain.; Center of Biomedical Investigation Network for Neurodegenerative Diseases, Madrid, Spain., Benzinger TLS; Department of Radiology, Washington University in St Louis, St Louis, Missouri., Betthauser TJ; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison.; Department of Medicine, University of Wisconsin, Madison., Bluma M; Center for Alzheimer Research, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Bombois S; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France., Bourgeat P; Australian eHealth Research Centre, CSIRO, Brisbane, Australia., Bouteloup V; Université de Bordeaux, Bordeaux, France.; Pôle de Santé Publique Centre Hospitalier Universitaire de Bordeaux, Inserm, UMR 1219, Inserm, CIC 1401-EC, Bordeaux, France., Braskie MN; Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles., Brendel M; Department of Nuclear Medicine, University Hospital of Munich, Munich, Germany.; Munich Cluster for Systems Neurology, Munich, Germany.; German Center for Neurodegenerative Diseases, Munich, Germany., Brickman AM; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York., Bryant N; University of California, Irvine., Bullich S; Life Molecular Imaging GmbH, Berlin, Germany., Carrillo MC; Medical and Scientific Relations, Alzheimer's Association, Chicago, Illinois., Casaletto K; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco., Cash DM; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, United Kingdom., Chang CC; Department of Neurology, Cognition and Aging Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Department of Medicine, National Sun Yat-Sen University, Taiwan., Chang HI; Department of Neurology, Cognition and Aging Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan., Chao Y; Department of Neuroscience, University of California, Berkeley., Chêne G; Université de Bordeaux, Bordeaux, France.; Pôle de Santé Publique Centre Hospitalier Universitaire de Bordeaux, Inserm, UMR 1219, Inserm, CIC 1401-EC, Bordeaux, France., Chételat G; Normandie Universitć, UNICAEN, INSERM, UA20, Neuropresage, Caen, France., Coath W; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, United Kingdom., Collij LE; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, the Netherlands., Colmant L; Department of Neurology Cliniques Universitaires Saint-Luc, Brussel, Belgium., Corrada MM; University of California, Irvine., Craft S; Wake Forest University School of Medicine, Winston-Salem, North Carolina., Dickerson BC; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston., Dubois B; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France., Dufouil C; Université de Bordeaux, Bordeaux, France.; Pôle de Santé Publique Centre Hospitalier Universitaire de Bordeaux, Inserm, UMR 1219, Inserm, CIC 1401-EC, Bordeaux, France., Fajardo A; Department of Psychiatry, McGill University, Montreal, Quebec, Canada., Farrar G; GE HealthCare Life Sciences, Amersham, United Kingdom., Fortea J; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain.; Center of Biomedical Investigation Network for Neurodegenerative Diseases, Madrid, Spain.; Barcelona Down Medical Center, Fundació Catalana de Síndrome de Down, Barcelona, Spain., Frings L; Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Frisoni GB; Laboratory of Neuroimaging of Aging, University of Geneva, Geneva, Switzerland.; Geneva Memory Centre, Department of Rehabilitation and Geriatrics, Geneva University Hospitals, Geneva, Switzerland., Gardner RC; Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, Israel., Garibotto V; Laboratory of Neuroimaging and Innovative Molecular Tracers, Geneva University Neurocentre and Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospitals, Geneva, Switzerland.; Centre for Biomedical Imaging, University of Geneva, Geneva, Switzerland., Gnörich JS; Department of Nuclear Medicine, University Hospital of Munich, Munich, Germany., Gordon BA; Department of Radiology, Washington University in St Louis, St Louis, Missouri., Gu Y; Samsung Medical Center, Seoul, Republic of Korea.; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea., Guan Y; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China., Guo T; Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, China., Hanseeuw BJ; Department of Neurology Cliniques Universitaires Saint-Luc, Brussel, Belgium., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Harrison TM; Department of Neuroscience, University of California, Berkeley., Huang Q; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China., Huang SH; Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan., Iaccarino L; Eli Lilly and Company, Indianapolis, Indiana., Ishii K; Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan., Ishi K; Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Jagust WJ; Department of Neuroscience, University of California, Berkeley., Johnson SC; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison.; Wisconsin Alzheimer's Institute, University of Wisconsin School of Medicine and Public Health, Madison., Kato T; National Center for Geriatrics and Gerontology, Aichi, Obu, Moriokamachi, Japan., Katsumi Y; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston., Kaye J; Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland., Koeppe RA; University of Michigan, Ann Arbor., Kolinger GD; Life Molecular Imaging GmbH, Berlin, Germany.; Lantheus Switzerland GmbH, Basel, Switzerland., Kramer JH; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco., Landau SM; Department of Neuroscience, University of California, Berkeley., Landeau B; Normandie Universitć, UNICAEN, INSERM, UA20, Neuropresage, Caen, France., Lao PJ; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York., Lee S; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea., Lleó A; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain.; Center of Biomedical Investigation Network for Neurodegenerative Diseases, Madrid, Spain., Lopresti BJ; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Lowe VJ; Department of Radiology, Mayo Clinic, Rochester, Minnesota., Luchsinger JA; Department of Medicine, Columbia University Irving Medical Center, New York, New York.; Department of Epidemiology, Columbia University Irving Medical Center, New York, New York., Malpetti M; Department of Clinical Neurosciences, University of Cambridge and Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom.; UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom., Mao X; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China., March A; American College of Radiology, Philadelphia, Pennsylvania., Masters CL; Alzheimer's Research Australia, University of Western Australia, Perth, Australia., Meyer PT; Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Mezenge F; Normandie Universitć, UNICAEN, INSERM, UA20, Neuropresage, Caen, France., Mormino EC; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Franquesa-Mullerat M; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain., Nakamura A; National Center for Geriatrics and Gerontology, Aichi, Obu, Moriokamachi, Japan., Nordberg A; Center for Alzheimer Research, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden., O'Brien JT; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom., O'Bryant SE; Institute for Translational Research, University of North Texas Health Science Center, Fort Worth., Pappas I; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles., Peretti DE; Laboratory of Neuroimaging and Innovative Molecular Tracers, Geneva University Neurocentre and Faculty of Medicine, University of Geneva, Geneva, Switzerland., Quenon L; Institute of Neuroscience, UCLouvain, Brussels, Belgium., Rowe CC; Department of Molecular Imaging, Austin Health, Heidelberg, Victoria, Australia.; Florey Institute of Neurosciences, University of Melbourne, Melbourne, Victoria, Australia., Rowe JB; Department of Clinical Neurosciences, University of Cambridge and Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom.; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, United Kingdom., Rudolph MD; Wake Forest University School of Medicine, Winston-Salem, North Carolina., Salvadó G; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Barcelona Beta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain., Schott JM; Indiana University School of Medicine, Indianapolis.; UK Dementia Research Institute at University College London, London, United Kingdom., Schwartz DL; Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland., Schwarz CG; Department of Radiology, Mayo Clinic, Rochester, Minnesota., Seo SW; Samsung Medical Center, Seoul, Republic of Korea., Shekari M; Barcelona Beta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain., Silbert LC; Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland., Smith R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Snyder HM; Medical and Scientific Relations, Alzheimer's Association, Chicago, Illinois., Sokolowski A; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Sperling RA; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston., Sun P; Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, China., Taggett JZ; Department of Neuroscience, University of California, Berkeley., Toga AW; Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden., Touroutoglou A; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston., Vaillancourt DE; Department of Applied Physiology and Kinesiology, 1Florida Alzheimer's Disease Research Center, University of Florida, Gainesville., van de Giessen E; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands., Vijverberg J; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands., Vemuri P; Department of Radiology, Mayo Clinic, Rochester, Minnesota., Villain N; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France., Villemagne VL; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Villeneuve S; Department of Psychiatry, McGill University, Montreal, Quebec, Canada., Wang WE; Department of Applied Physiology and Kinesiology, 1Florida Alzheimer's Disease Research Center, University of Florida, Gainesville., Weiner M; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco., Woodworth D; University of California, Irvine., Xiao C; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles., Xie F; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China., Yoon Y; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea., Young CB; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California.; Department of Radiology, University of California, Davis.; Department of Neurology, University of California, Davis., Yun M; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Corporate Authors: Meta-Centiloid Study Group, A4, ABIDE, ADNI*, ADNI-DoD, AgeWell, AIBL, AMYPAD, BACS, BATON, BIOCARD, BLSA, BioFINDER-2, BrANCH, CPAS, DETECT-AD, GEMS, GHABS, HABS, HABS-HD, IDEAS, IMAP, INSIGHT-preAD, Insight46, K-ROAD, LEADS, MCSA, MULNIAD, MEMENTO, SCAN, PREVENT-AD, SPIN, Severanc
Source: JAMA [JAMA] 2026 Jul 13. Date of Electronic Publication: 2026 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
  Label: Title
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  Data: Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Blazhenets+G%22">Blazhenets G</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Soleimani-Meigooni+DN%22">Soleimani-Meigooni DN</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, California.<br /><searchLink fieldCode="AU" term="%22Chiotis+K%22">Chiotis K</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.; Center for Alzheimer Research, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Allen+IE%22">Allen IE</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Rabinovici+GD%22">Rabinovici GD</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.; Department of Radiology and Biomedical Imaging, University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22La+Joie+R%22">La Joie R</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Apostolova+LG%22">Apostolova LG</searchLink>; Indiana University School of Medicine, Indianapolis.<br /><searchLink fieldCode="AU" term="%22Asken+BM%22">Asken BM</searchLink>; Department of Clinical and Health Psychology, 1Florida Alzheimer's Disease Research Center, University of Florida, Gainesville.<br /><searchLink fieldCode="AU" term="%22Bejanin+A%22">Bejanin A</searchLink>; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain.; Center of Biomedical Investigation Network for Neurodegenerative Diseases, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Benzinger+TLS%22">Benzinger TLS</searchLink>; Department of Radiology, Washington University in St Louis, St Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Betthauser+TJ%22">Betthauser TJ</searchLink>; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison.; Department of Medicine, University of Wisconsin, Madison.<br /><searchLink fieldCode="AU" term="%22Bluma+M%22">Bluma M</searchLink>; Center for Alzheimer Research, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Bombois+S%22">Bombois S</searchLink>; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bourgeat+P%22">Bourgeat P</searchLink>; Australian eHealth Research Centre, CSIRO, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Bouteloup+V%22">Bouteloup V</searchLink>; Université de Bordeaux, Bordeaux, France.; Pôle de Santé Publique Centre Hospitalier Universitaire de Bordeaux, Inserm, UMR 1219, Inserm, CIC 1401-EC, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Braskie+MN%22">Braskie MN</searchLink>; Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Brendel+M%22">Brendel M</searchLink>; Department of Nuclear Medicine, University Hospital of Munich, Munich, Germany.; Munich Cluster for Systems Neurology, Munich, Germany.; German Center for Neurodegenerative Diseases, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Brickman+AM%22">Brickman AM</searchLink>; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Bryant+N%22">Bryant N</searchLink>; University of California, Irvine.<br /><searchLink fieldCode="AU" term="%22Bullich+S%22">Bullich S</searchLink>; Life Molecular Imaging GmbH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Carrillo+MC%22">Carrillo MC</searchLink>; Medical and Scientific Relations, Alzheimer's Association, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Casaletto+K%22">Casaletto K</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Cash+DM%22">Cash DM</searchLink>; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chang+CC%22">Chang CC</searchLink>; Department of Neurology, Cognition and Aging Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Department of Medicine, National Sun Yat-Sen University, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+HI%22">Chang HI</searchLink>; Department of Neurology, Cognition and Aging Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chao+Y%22">Chao Y</searchLink>; Department of Neuroscience, University of California, Berkeley.<br /><searchLink fieldCode="AU" term="%22Chêne+G%22">Chêne G</searchLink>; Université de Bordeaux, Bordeaux, France.; Pôle de Santé Publique Centre Hospitalier Universitaire de Bordeaux, Inserm, UMR 1219, Inserm, CIC 1401-EC, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Chételat+G%22">Chételat G</searchLink>; Normandie Universitć, UNICAEN, INSERM, UA20, Neuropresage, Caen, France.<br /><searchLink fieldCode="AU" term="%22Coath+W%22">Coath W</searchLink>; Dementia Research Centre, UCL Queen Square Institute of Neurology, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Collij+LE%22">Collij LE</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain Imaging, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Colmant+L%22">Colmant L</searchLink>; Department of Neurology Cliniques Universitaires Saint-Luc, Brussel, Belgium.<br /><searchLink fieldCode="AU" term="%22Corrada+MM%22">Corrada MM</searchLink>; University of California, Irvine.<br /><searchLink fieldCode="AU" term="%22Craft+S%22">Craft S</searchLink>; Wake Forest University School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Dickerson+BC%22">Dickerson BC</searchLink>; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Dubois+B%22">Dubois B</searchLink>; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dufouil+C%22">Dufouil C</searchLink>; Université de Bordeaux, Bordeaux, France.; Pôle de Santé Publique Centre Hospitalier Universitaire de Bordeaux, Inserm, UMR 1219, Inserm, CIC 1401-EC, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Fajardo+A%22">Fajardo A</searchLink>; Department of Psychiatry, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Farrar+G%22">Farrar G</searchLink>; GE HealthCare Life Sciences, Amersham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fortea+J%22">Fortea J</searchLink>; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain.; Center of Biomedical Investigation Network for Neurodegenerative Diseases, Madrid, Spain.; Barcelona Down Medical Center, Fundació Catalana de Síndrome de Down, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Frings+L%22">Frings L</searchLink>; Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Frisoni+GB%22">Frisoni GB</searchLink>; Laboratory of Neuroimaging of Aging, University of Geneva, Geneva, Switzerland.; Geneva Memory Centre, Department of Rehabilitation and Geriatrics, Geneva University Hospitals, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gardner+RC%22">Gardner RC</searchLink>; Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, Israel.<br /><searchLink fieldCode="AU" term="%22Garibotto+V%22">Garibotto V</searchLink>; Laboratory of Neuroimaging and Innovative Molecular Tracers, Geneva University Neurocentre and Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospitals, Geneva, Switzerland.; Centre for Biomedical Imaging, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gnörich+JS%22">Gnörich JS</searchLink>; Department of Nuclear Medicine, University Hospital of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gordon+BA%22">Gordon BA</searchLink>; Department of Radiology, Washington University in St Louis, St Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Gu+Y%22">Gu Y</searchLink>; Samsung Medical Center, Seoul, Republic of Korea.; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Guan+Y%22">Guan Y</searchLink>; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Guo+T%22">Guo T</searchLink>; Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Hanseeuw+BJ%22">Hanseeuw BJ</searchLink>; Department of Neurology Cliniques Universitaires Saint-Luc, Brussel, Belgium.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Harrison+TM%22">Harrison TM</searchLink>; Department of Neuroscience, University of California, Berkeley.<br /><searchLink fieldCode="AU" term="%22Huang+Q%22">Huang Q</searchLink>; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+SH%22">Huang SH</searchLink>; Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Iaccarino+L%22">Iaccarino L</searchLink>; Eli Lilly and Company, Indianapolis, Indiana.<br /><searchLink fieldCode="AU" term="%22Ishii+K%22">Ishii K</searchLink>; Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ishi+K%22">Ishi K</searchLink>; Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Jagust+WJ%22">Jagust WJ</searchLink>; Department of Neuroscience, University of California, Berkeley.<br /><searchLink fieldCode="AU" term="%22Johnson+SC%22">Johnson SC</searchLink>; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison.; Wisconsin Alzheimer's Institute, University of Wisconsin School of Medicine and Public Health, Madison.<br /><searchLink fieldCode="AU" term="%22Kato+T%22">Kato T</searchLink>; National Center for Geriatrics and Gerontology, Aichi, Obu, Moriokamachi, Japan.<br /><searchLink fieldCode="AU" term="%22Katsumi+Y%22">Katsumi Y</searchLink>; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Kaye+J%22">Kaye J</searchLink>; Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland.<br /><searchLink fieldCode="AU" term="%22Koeppe+RA%22">Koeppe RA</searchLink>; University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Kolinger+GD%22">Kolinger GD</searchLink>; Life Molecular Imaging GmbH, Berlin, Germany.; Lantheus Switzerland GmbH, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kramer+JH%22">Kramer JH</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Landau+SM%22">Landau SM</searchLink>; Department of Neuroscience, University of California, Berkeley.<br /><searchLink fieldCode="AU" term="%22Landeau+B%22">Landeau B</searchLink>; Normandie Universitć, UNICAEN, INSERM, UA20, Neuropresage, Caen, France.<br /><searchLink fieldCode="AU" term="%22Lao+PJ%22">Lao PJ</searchLink>; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lleó+A%22">Lleó A</searchLink>; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain.; Center of Biomedical Investigation Network for Neurodegenerative Diseases, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Lopresti+BJ%22">Lopresti BJ</searchLink>; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Lowe+VJ%22">Lowe VJ</searchLink>; Department of Radiology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Luchsinger+JA%22">Luchsinger JA</searchLink>; Department of Medicine, Columbia University Irving Medical Center, New York, New York.; Department of Epidemiology, Columbia University Irving Medical Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Malpetti+M%22">Malpetti M</searchLink>; Department of Clinical Neurosciences, University of Cambridge and Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom.; UK Dementia Research Institute at University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mao+X%22">Mao X</searchLink>; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22March+A%22">March A</searchLink>; American College of Radiology, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Masters+CL%22">Masters CL</searchLink>; Alzheimer's Research Australia, University of Western Australia, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Meyer+PT%22">Meyer PT</searchLink>; Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mezenge+F%22">Mezenge F</searchLink>; Normandie Universitć, UNICAEN, INSERM, UA20, Neuropresage, Caen, France.<br /><searchLink fieldCode="AU" term="%22Mormino+EC%22">Mormino EC</searchLink>; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Franquesa-Mullerat+M%22">Franquesa-Mullerat M</searchLink>; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB SANT PAU), Facultad de Medicina - Universitat Autònoma de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Nakamura+A%22">Nakamura A</searchLink>; National Center for Geriatrics and Gerontology, Aichi, Obu, Moriokamachi, Japan.<br /><searchLink fieldCode="AU" term="%22Nordberg+A%22">Nordberg A</searchLink>; Center for Alzheimer Research, Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22O'Brien+JT%22">O'Brien JT</searchLink>; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22O'Bryant+SE%22">O'Bryant SE</searchLink>; Institute for Translational Research, University of North Texas Health Science Center, Fort Worth.<br /><searchLink fieldCode="AU" term="%22Pappas+I%22">Pappas I</searchLink>; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Peretti+DE%22">Peretti DE</searchLink>; Laboratory of Neuroimaging and Innovative Molecular Tracers, Geneva University Neurocentre and Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Quenon+L%22">Quenon L</searchLink>; Institute of Neuroscience, UCLouvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Rowe+CC%22">Rowe CC</searchLink>; Department of Molecular Imaging, Austin Health, Heidelberg, Victoria, Australia.; Florey Institute of Neurosciences, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Rowe+JB%22">Rowe JB</searchLink>; Department of Clinical Neurosciences, University of Cambridge and Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom.; Medical Research Council Cognition and Brain Sciences Unit, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rudolph+MD%22">Rudolph MD</searchLink>; Wake Forest University School of Medicine, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Salvadó+G%22">Salvadó G</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Barcelona Beta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Schott+JM%22">Schott JM</searchLink>; Indiana University School of Medicine, Indianapolis.; UK Dementia Research Institute at University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Schwartz+DL%22">Schwartz DL</searchLink>; Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland.<br /><searchLink fieldCode="AU" term="%22Schwarz+CG%22">Schwarz CG</searchLink>; Department of Radiology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Seo+SW%22">Seo SW</searchLink>; Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shekari+M%22">Shekari M</searchLink>; Barcelona Beta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Silbert+LC%22">Silbert LC</searchLink>; Layton Aging and Alzheimer's Disease Center, Oregon Health & Science University, Portland.<br /><searchLink fieldCode="AU" term="%22Smith+R%22">Smith R</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Snyder+HM%22">Snyder HM</searchLink>; Medical and Scientific Relations, Alzheimer's Association, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Sokolowski+A%22">Sokolowski A</searchLink>; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Sperling+RA%22">Sperling RA</searchLink>; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Sun+P%22">Sun P</searchLink>; Institute of Neurological and Psychiatric Disorders, Shenzhen Bay Laboratory, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Taggett+JZ%22">Taggett JZ</searchLink>; Department of Neuroscience, University of California, Berkeley.<br /><searchLink fieldCode="AU" term="%22Toga+AW%22">Toga AW</searchLink>; Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Touroutoglou+A%22">Touroutoglou A</searchLink>; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Vaillancourt+DE%22">Vaillancourt DE</searchLink>; Department of Applied Physiology and Kinesiology, 1Florida Alzheimer's Disease Research Center, University of Florida, Gainesville.<br /><searchLink fieldCode="AU" term="%22van+de+Giessen+E%22">van de Giessen E</searchLink>; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vijverberg+J%22">Vijverberg J</searchLink>; Department of Radiology and Nuclear Medicine, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vemuri+P%22">Vemuri P</searchLink>; Department of Radiology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Villain+N%22">Villain N</searchLink>; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Villemagne+VL%22">Villemagne VL</searchLink>; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Villeneuve+S%22">Villeneuve S</searchLink>; Department of Psychiatry, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+WE%22">Wang WE</searchLink>; Department of Applied Physiology and Kinesiology, 1Florida Alzheimer's Disease Research Center, University of Florida, Gainesville.<br /><searchLink fieldCode="AU" term="%22Weiner+M%22">Weiner M</searchLink>; Edward and Pearl Fein Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco.<br /><searchLink fieldCode="AU" term="%22Woodworth+D%22">Woodworth D</searchLink>; University of California, Irvine.<br /><searchLink fieldCode="AU" term="%22Xiao+C%22">Xiao C</searchLink>; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Xie+F%22">Xie F</searchLink>; Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yoon+Y%22">Yoon Y</searchLink>; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Young+CB%22">Young CB</searchLink>; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California.; Department of Radiology, University of California, Davis.; Department of Neurology, University of California, Davis.<br /><searchLink fieldCode="AU" term="%22Yun+M%22">Yun M</searchLink>; Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%227501160%22">JAMA</searchLink> [JAMA] 2026 Jul 13. <i>Date of Electronic Publication: </i>2026 Jul 13.
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        Value: 10.1001/jama.2026.13116
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      – TitleFull: Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
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      – PersonEntity:
          Name:
            NameFull: O'Brien JT
      – PersonEntity:
          Name:
            NameFull: O'Bryant SE
      – PersonEntity:
          Name:
            NameFull: Pappas I
      – PersonEntity:
          Name:
            NameFull: Peretti DE
      – PersonEntity:
          Name:
            NameFull: Quenon L
      – PersonEntity:
          Name:
            NameFull: Rowe CC
      – PersonEntity:
          Name:
            NameFull: Rowe JB
      – PersonEntity:
          Name:
            NameFull: Rudolph MD
      – PersonEntity:
          Name:
            NameFull: Salvadó G
      – PersonEntity:
          Name:
            NameFull: Schott JM
      – PersonEntity:
          Name:
            NameFull: Schwartz DL
      – PersonEntity:
          Name:
            NameFull: Schwarz CG
      – PersonEntity:
          Name:
            NameFull: Seo SW
      – PersonEntity:
          Name:
            NameFull: Shekari M
      – PersonEntity:
          Name:
            NameFull: Silbert LC
      – PersonEntity:
          Name:
            NameFull: Smith R
      – PersonEntity:
          Name:
            NameFull: Snyder HM
      – PersonEntity:
          Name:
            NameFull: Sokolowski A
      – PersonEntity:
          Name:
            NameFull: Sperling RA
      – PersonEntity:
          Name:
            NameFull: Sun P
      – PersonEntity:
          Name:
            NameFull: Taggett JZ
      – PersonEntity:
          Name:
            NameFull: Toga AW
      – PersonEntity:
          Name:
            NameFull: Touroutoglou A
      – PersonEntity:
          Name:
            NameFull: Vaillancourt DE
      – PersonEntity:
          Name:
            NameFull: van de Giessen E
      – PersonEntity:
          Name:
            NameFull: Vijverberg J
      – PersonEntity:
          Name:
            NameFull: Vemuri P
      – PersonEntity:
          Name:
            NameFull: Villain N
      – PersonEntity:
          Name:
            NameFull: Villemagne VL
      – PersonEntity:
          Name:
            NameFull: Villeneuve S
      – PersonEntity:
          Name:
            NameFull: Wang WE
      – PersonEntity:
          Name:
            NameFull: Weiner M
      – PersonEntity:
          Name:
            NameFull: Woodworth D
      – PersonEntity:
          Name:
            NameFull: Xiao C
      – PersonEntity:
          Name:
            NameFull: Xie F
      – PersonEntity:
          Name:
            NameFull: Yoon Y
      – PersonEntity:
          Name:
            NameFull: Young CB
      – PersonEntity:
          Name:
            NameFull: Yun M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 13
              M: 07
              Text: 2026 Jul 13
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1538-3598
          Titles:
            – TitleFull: JAMA
              Type: main
ResultId 1