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Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow: A Randomized Double-Blind Placebo-Controlled Mechanistic Study.

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Title: Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow: A Randomized Double-Blind Placebo-Controlled Mechanistic Study.
Authors: Mahendiran T; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland., Wilgenhof A; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy., Corradetti S; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Viscusi M; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Heyse A; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., De Wolf T; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Aroudj N; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Browaeys S; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Claessens N; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Cobbaut I; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., De Block L; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., De Wolf K; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Delacroix H; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Girukwishaka E; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Mathieu E; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Van Cutsem K; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Van De Velde C; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Van Der Kelen P; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Verbeken L; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., De Gend I; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., De Vulder I; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Haeleydt N; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Heremans S; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Rooselaers K; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Verbeurgt A; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Verhelst D; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Van Laer E; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Nelis O; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Storozhenko T; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Prevention and Treatment of Emergency Conditions, L.T. Malaya Therapy National Institute NAMSU, Kharkiv, Ukraine., Buytaert D; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Sonck J; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Johnson NP; Division of Cardiology, Department of Medicine, McGovern Medical School at University of Texas Health and Memorial Hermann Hospital, Houston, Texas, USA., Collet C; Cardiovascular Center Aalst, AZORG, Aalst, Belgium., Jüni P; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., De Bruyne B; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland. Electronic address: bernard.de.bruyne@gammas.be.
Source: JACC. Cardiovascular interventions [JACC Cardiovasc Interv] 2026 Jul 13; Vol. 19 (13), pp. 1748-1762. Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101467004 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-7605 (Electronic) Linking ISSN: 19368798 NLM ISO Abbreviation: JACC Cardiovasc Interv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow: A Randomized Double-Blind Placebo-Controlled Mechanistic Study.
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  Data: <searchLink fieldCode="AU" term="%22Mahendiran+T%22">Mahendiran T</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wilgenhof+A%22">Wilgenhof A</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Corradetti+S%22">Corradetti S</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Viscusi+M%22">Viscusi M</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Heyse+A%22">Heyse A</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Wolf+T%22">De Wolf T</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Aroudj+N%22">Aroudj N</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Browaeys+S%22">Browaeys S</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Claessens+N%22">Claessens N</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Cobbaut+I%22">Cobbaut I</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Block+L%22">De Block L</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Wolf+K%22">De Wolf K</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Delacroix+H%22">Delacroix H</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Girukwishaka+E%22">Girukwishaka E</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Mathieu+E%22">Mathieu E</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Cutsem+K%22">Van Cutsem K</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+De+Velde+C%22">Van De Velde C</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Der+Kelen+P%22">Van Der Kelen P</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Verbeken+L%22">Verbeken L</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Gend+I%22">De Gend I</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Vulder+I%22">De Vulder I</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Haeleydt+N%22">Haeleydt N</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Heremans+S%22">Heremans S</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Rooselaers+K%22">Rooselaers K</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Verbeurgt+A%22">Verbeurgt A</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Verhelst+D%22">Verhelst D</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Laer+E%22">Van Laer E</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Nelis+O%22">Nelis O</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Storozhenko+T%22">Storozhenko T</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Prevention and Treatment of Emergency Conditions, L.T. Malaya Therapy National Institute NAMSU, Kharkiv, Ukraine.<br /><searchLink fieldCode="AU" term="%22Buytaert+D%22">Buytaert D</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Sonck+J%22">Sonck J</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Johnson+NP%22">Johnson NP</searchLink>; Division of Cardiology, Department of Medicine, McGovern Medical School at University of Texas Health and Memorial Hermann Hospital, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Collet+C%22">Collet C</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium.<br /><searchLink fieldCode="AU" term="%22Jüni+P%22">Jüni P</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22De+Bruyne+B%22">De Bruyne B</searchLink>; Cardiovascular Center Aalst, AZORG, Aalst, Belgium; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland. Electronic address: bernard.de.bruyne@gammas.be.
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  Data: <searchLink fieldCode="JN" term="%22101467004%22">JACC. Cardiovascular interventions</searchLink> [JACC Cardiovasc Interv] 2026 Jul 13; Vol. 19 (13), pp. 1748-1762. <i>Date of Electronic Publication: </i>2026 May 11.
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