Clinical Meaningfulness of the Composite Endpoint, COPDCompEx, in Defining Exacerbations and Worsening of COPD: A Post Hoc Analysis of 4 Clinical Interventional Studies of COPD.

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Title: Clinical Meaningfulness of the Composite Endpoint, COPDCompEx, in Defining Exacerbations and Worsening of COPD: A Post Hoc Analysis of 4 Clinical Interventional Studies of COPD.
Authors: Tal-Singer R; Global Allergy and Airways Patient Platform, Vienna, Austria., Vogelmeier CF; Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Marburg, Germany., Bolton C; Early R&D, AstraZeneca, Cambridge, UK., Bengtsson T; StatMind Statistical and Mathematical Modelling, Innovation, and Design AB, Lund, Sweden., Peterson S; StatMind Statistical and Mathematical Modelling, Innovation, and Design AB, Lund, Sweden., Sidaway M; Late Respiratory and Immunology Clinical Development, AstraZeneca, Gothenburg, Sweden., Da Silva CA; Early Respiratory and Immunology Clinical Development, AstraZeneca, Gothenburg, Sweden.; Digital Health Strategy & Implementation, Evinova, Gothenburg, Sweden.
Source: International journal of chronic obstructive pulmonary disease [Int J Chron Obstruct Pulmon Dis] 2026 Jul 09; Vol. 21, pp. 603089. Date of Electronic Publication: 2026 Jul 09 (Print Publication: 2026).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101273481 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2005 (Electronic) Linking ISSN: 11769106 NLM ISO Abbreviation: Int J Chron Obstruct Pulmon Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical Meaningfulness of the Composite Endpoint, COPDCompEx, in Defining Exacerbations and Worsening of COPD: A Post Hoc Analysis of 4 Clinical Interventional Studies of COPD.
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  Data: <searchLink fieldCode="AU" term="%22Tal-Singer+R%22">Tal-Singer R</searchLink>; Global Allergy and Airways Patient Platform, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Vogelmeier+CF%22">Vogelmeier CF</searchLink>; Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bolton+C%22">Bolton C</searchLink>; Early R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bengtsson+T%22">Bengtsson T</searchLink>; StatMind Statistical and Mathematical Modelling, Innovation, and Design AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Peterson+S%22">Peterson S</searchLink>; StatMind Statistical and Mathematical Modelling, Innovation, and Design AB, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Sidaway+M%22">Sidaway M</searchLink>; Late Respiratory and Immunology Clinical Development, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Da+Silva+CA%22">Da Silva CA</searchLink>; Early Respiratory and Immunology Clinical Development, AstraZeneca, Gothenburg, Sweden.; Digital Health Strategy & Implementation, Evinova, Gothenburg, Sweden.
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  Data: <searchLink fieldCode="JN" term="%22101273481%22">International journal of chronic obstructive pulmonary disease</searchLink> [Int J Chron Obstruct Pulmon Dis] 2026 Jul 09; Vol. 21, pp. 603089. <i>Date of Electronic Publication: </i>2026 Jul 09 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22DOVE+Medical+Press%22">DOVE Medical Press </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101273481 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1178-2005 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211769106%22">11769106 </searchLink><i>NLM ISO Abbreviation: </i>Int J Chron Obstruct Pulmon Dis <i>Subsets: </i>MEDLINE
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        Value: 10.2147/COPD.S603089
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      – TitleFull: Clinical Meaningfulness of the Composite Endpoint, COPDCompEx, in Defining Exacerbations and Worsening of COPD: A Post Hoc Analysis of 4 Clinical Interventional Studies of COPD.
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              Text: 2026 Jul 09
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