Cell line identity rather than medium composition determines transcriptomic profiles of HepaRG and HuH7 cells cultured in chemically defined or serum-based media: comparison with primary human hepatocytes.
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| Title: | Cell line identity rather than medium composition determines transcriptomic profiles of HepaRG and HuH7 cells cultured in chemically defined or serum-based media: comparison with primary human hepatocytes. |
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| Authors: | Ali ASM; Chair of Applied Biochemistry, Institute of Biotechnology, Technische Universität Berlin, 10623, Berlin, Germany., Sprenger H; Department Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), 10589, Berlin, Germany., Braeuning A; Department Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), 10589, Berlin, Germany., Kurreck J; Chair of Applied Biochemistry, Institute of Biotechnology, Technische Universität Berlin, 10623, Berlin, Germany. jens.kurreck@tu-berlin.de. |
| Source: | Archives of toxicology [Arch Toxicol] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1432-0738 |
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| DOI: | 10.1007/s00204-026-04502-z |