Acinetobacter baumannii lipooligosaccharide core region promotes CD14-dependent TLR4 endocytosis and enhances pathogenicity through interferon-β production.

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Title: Acinetobacter baumannii lipooligosaccharide core region promotes CD14-dependent TLR4 endocytosis and enhances pathogenicity through interferon-β production.
Authors: Lee YT; Department of Emergency Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.; Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chen TL; Graduate Institute of Life Sciences, College of Biomedical Sciences, National Defense Medical University, Taipei, Taiwan., Kuo SC; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County, Taiwan., Liu YH; Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Lee MC; School of Public Health, National Defense Medical University, Taipei, Taiwan., Chuang MF; Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Tan MC; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County, Taiwan., Lee IM; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, Taiwan.; Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan., Yang YS; Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Wang YC; Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.
Source: PLoS pathogens [PLoS Pathog] 2026 Jul 14; Vol. 22 (7), pp. e1014364. Date of Electronic Publication: 2026 Jul 14 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7374
DOI:10.1371/journal.ppat.1014364