Harmonized metagenomic signatures of the gut microbiome reveal robust species, functions, and strain links to inflammatory bowel disease.

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Title: Harmonized metagenomic signatures of the gut microbiome reveal robust species, functions, and strain links to inflammatory bowel disease.
Authors: Thompson KN; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Ma S; Department of Biostatistics, Vanderbilt University Medical Center, Vanderbilt, TN, USA., Bhosle A; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Nickols WA; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Shen J; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Ghazi AR; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Dang NH; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Zhang Y; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Nzabarushimana E; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Kim H; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Xavier RJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Chan AT; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Franzosa EA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Huttenhower C; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: chuttenh@hsph.harvard.edu., Nguyen LH; Harvard Chan Microbiome in Public Health Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: lnguyen24@mgh.harvard.edu.
Source: Gastroenterology [Gastroenterology] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-0012
DOI:10.1053/j.gastro.2026.06.023