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Slow-SPEED: protocol for three randomised trials of remotely delivered exercise to prevent Parkinson's disease.

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Title: Slow-SPEED: protocol for three randomised trials of remotely delivered exercise to prevent Parkinson's disease.
Authors: Oosterhof TH; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Mitchell E; Center for Preventive Neurology Wolfson Institute of Population Health, Queen Mary University of London, London, UK., Ascherio A; Department of Nutrition and Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Aslibekyan S; 23andMe Research Institute, Palo Alto, CA, USA., Azoidou V; Center for Preventive Neurology Wolfson Institute of Population Health, Queen Mary University of London, London, UK., Beasley K; Davis Phinney Foundation, Louisville, CO, USA., Ben-Shlomo Y; Population Health Sciences, Bristol Medical School, Bristol, UK., Bunnik E; Department of Public Health, Medical Ethics, Philosophy and History of Medicine Programme, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Carroll C; Translational and Clinical Research Institute, Newcastle University National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre (BRC), Newcastle University, Newcastle upon Tyne, UK., Chahine L; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Corcos D; Department of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, USA., Janssen Daalen JM; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., van Dijk KD; Stichting Epilepsie Instellingen Nederland (SEIN), Heemstede, The Netherlands.; Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Anatomy and Neurosciences, Amsterdam, The Netherlands., Dijkstra BW; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Dommershuijsen L; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Dorsey R; Department of Neurology and Center for Health and Technology, University of Rochester, Rochester, NY, USA.; Center for the Brain & Environment, Atria Research and Global Health Institute, New York, NY, USA., Evers LJW; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Helmich RC; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Johansson M; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.; Institut du Cerveau - Paris Brain Institute, Movement Investigations and Therapeutics Team (MOV'IT), Center for NeuroImaging Research (CENIR), Sorbonne University, Pitié-Salpêtrière Hospital, Paris, France., Norcliffe-Kaufmann L; 23andMe Research Institute, Palo Alto, CA, USA., Keavney J; Parkinson's Foundation, Parkinson's Advocates in Research Program, Pendergrass, GA, USA., Klein C; Institute of Neurogenetics, University of Luebeck and University Hospital Schleswig-Holstein, Luebeck, Germany., Kmiecik MJ; 23andMe Research Institute, Palo Alto, CA, USA., Kustermann T; Roche Pharma Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Macklin EA; Massachusetts General Hospital Biostatistics, Massachusetts General Hospital and Department of Neurology, Harvard Medical School, Boston, USA., Marek K; Institute for Neurodegenerative Disorders, New Haven, CT, USA., Meles SK; Department of Neurology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Overeem S; Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands., Philpott CM; Norfolk Smell & Taste Clinic, James Paget University Hospital, Gorleston, Norfolk, UK.; Rhinology & Olfactology Research Group, Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK., Pijpers A; Sleep Medicine Center Kempenhaeghe, Heeze, The Netherlands., Postuma RB; The Neuro, Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada., Rowbotham HM; 23andMe Research Institute, Palo Alto, CA, USA., Schootemeijer S; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, the Netherlands., Schwarzschild MA; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, USA., Simuni T; Northwestern University Feinberg School of Medicine, Department of Neurology, Chicago, IL, USA., Sommerauer M; Center of Neurology, Department of Parkinson's, Sleep and Movement Disorders, University Hospital Bonn, Bonn, Germany & German Center for Neurodegenerative Diseases, Bonn, Germany., Stefani A; Center for Sleep Medicine, Department of Neurology, Medical University Innsbruck, Innsbruck, Austria., Steidel K; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.; Department of Neurology, Philipps University Marburg, Marburg, Germany., Verbeek M; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., van der Vliet R; Department of Neuroscience and Neurology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands., de Vries NM; Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., van de Warrenburg B; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Wyse RK; Cure Parkinson's, London, UK., Bloem BR; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands., Schneider RB; Department of Neurology and Center for Health and Technology, University of Rochester, Rochester, NY, USA., Noyce AJ; Center for Preventive Neurology Wolfson Institute of Population Health, Queen Mary University of London, London, UK., Darweesh SKL; Center of Expertise for Parkinson and Movement Disorders, Department of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands. sirwan.darweesh@radboudumc.nl.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis
Database: MEDLINE Ultimate
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