MIT-001, a Mitochondria-Targeted ROS Scavenger, Ameliorates DSS-Induced Colitis and Is Associated with Reduced HMGB1 and IL-1β Expression.

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Title: MIT-001, a Mitochondria-Targeted ROS Scavenger, Ameliorates DSS-Induced Colitis and Is Associated with Reduced HMGB1 and IL-1β Expression.
Authors: Kim D; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Kim SH; Mitoimmune Therapeutics Inc., Seoul 05836, Republic of Korea., Choe JW; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Kim SY; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Hyun JJ; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Jung SW; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Jung YK; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Yim HJ; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea., Koo JS; Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Republic of Korea.; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Jul 06; Vol. 27 (13). Date of Electronic Publication: 2026 Jul 06.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1422-0067
DOI:10.3390/ijms27136051